acyl

Methyl-PEG4-acyl chloride is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Azido-PEG4-acyl chloride is a PROTAC linker that falls under the PEG category, utilized in the synthesis of PROTAC molecules. As a click chemistry reagent, it contains an Azide group, allowing it to undergo copper-catalyzed azide-alkyne cycloaddition reactions (CuAAC) with molecules bearing an Alkyne group. Additionally, it can partake in strain-promoted azide-alkyne cycloaddition reactions (SPAAC) with molecules containing DBCO or BCN groups.

Benzyl-PEG4-acyl chloride is a PEG-based PROTAC linker used in the synthesis of PROTAC molecules.