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By Target- Bcr-Abl
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Results for "
abl 001
" in TargetMol Product Catalog- Inhibitors & Agonists2
- Dye Reagents1
Asciminib
Cited
ABL001
T51771492952-76-7
Asciminib (ABL001) (ABL001) is a potent and selective Bcr-Abl inhibitor (Kd: 0.5–0.8nM).
- $57
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QTY
CitedAsciminib hydrochloride
ABL-001 hydrochloride, ABL001 hydrochloride
T632262119669-71-3
Asciminib hydrochloride is described as a "STAMP inhibitor," specifically targeting the ABL myristoyl pocket, Asciminib hydrochloride, marketed as Scemblix, are applied in research in Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML) by binding to the allosteric site of wild-type ABL N-terminus, which is myristoylated, whereas the ABL fusion protein lacks this domain, enabling selective modulation of oncogenic signaling pathways and serving as a targeted therapeutic tool in hematologic cancer research.
- $55
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