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Results for "
abatacept
" in TargetMol Product Catalog.- Inhibitors & Agonists1
- Inhibitory Antibodies1
- Antibody Products2
Abatacept
CTLA4lg, BMS-188667
T10218332348-12-6
Abatacept is a soluble recombinant fusion protein, which consists of extracellular domain of human CTLA-4 and human Fc segment. Abatacept specifically blocks CD28-mediated costimulatory signals by binding to CD80 and CD86 on the surface of antigen presenting cells with high affinity, thus inhibiting T cell activation. Abatacept is often used to study rheumatoid arthritis, autoimmune reaction and immune disorder caused by LRBA deficiency.
- $813
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