a-d-glucosidase

α-Glucosidase (α-D-Glucosidase) is a carbohydrate hydrolyzing enzyme that catalyzes the release of α-glucose from the non-reducing end of the substrate, playing a vital role in glucose absorption by the small intestine. Inhibiting α-Glucosidase effectively manages non-insulin-dependent diabetes mellitus (NIDDM).

Naringinase is a hydrolytic enzymatic complex that exhibits α-L-rhamnosidase and β-D-glucosidase activities. It is widely found in nature and is primarily utilized for the biotransformation of steroids, antibiotics, and glycosides.

Glycosidase-IN-1 is a glycosidase inhibitor synthesized from D-mannose with hypoglycemic activity. It can be used to synthesize some immunosuppressive agents and β-glucosidase inhibitors.

Afegostat D-Tartrate is a pharmacological chaperone that binds specifically and reversibly with high affinity to acid-β-glucosidase (GCase) in the endoplasmic reticulum.

4-Nitrophenyl β-D-cellobioside is a disaccharide and an enzyme substrate. It has been used to characterize the function of endoglucanase 1 from T. harzianum, β-glucosidase from T. xylanolyticum, and glycoside hydrolase family 3 (GH3) aryl β-glucosidases from A. oryzae.

Daucosterol (Sitogluside) has proliferation-enhancing activity, may be involved in the IGF1-AKT pathway. Daucosterol(β-Sitosterol β-D-glucoside) has efficient and inexpensive neuroprotectant effect, to contribute to IGF1-like activity, could be potentially developed as a medicine for ischemic stroke treatment.

Prunetin 5-O-β-D-glucopyranoside, an isoflavone obtained from Potentilla astracanica extracts, is a potent uncompetitive inhibitor of α-glucosidase (IC 50 = 56.05 μg/mL). It serves as a valuable tool for type-2 diabetes research.

Isorhamnetin-3-O-glucoside (Isorhamnetin-3-O-beta-D-Glucoside) inhibits the activity of alpha-glucosidase from rat intestine; it exhibits a potent rat lens aldose reductase (RLAR) inhibition in vitro, its IC(50) being 1.4 microM and has inhibitory effects of sorbitol accumulation, suggests that it is a leading compound for further study as a new drug for the prevention and/or treatment of diabetes and its complications.

pNPG-1(4-Nitrophenyl β-D-glucuronide) is a glucuronide monosaccharide derivative that is a chromogenic substrate for β-glucosidase.

2-Nitrophenyl a-D-glucopyranoside is a substrate of β-glucosidase [1].

4-Methylumbelliferyl-α-D-Glucopyranoside (4MU-αGlc) is a pH-dependent α-glucosidase fluorometric substrate, a biomarker for Fabry and Pompe diseases, quantifying α-glucosidase activity in infant blood spots.

alpha-Spinasterol glucoside (α-Spinasterol-3-O-β-D-glucoside) is a natural sterol glucoside exhibiting weak inhibitory activity against alpha-glucosidase (IC₅₀ = 75.9 µM).

Apigenin 5-O-beta-D-glucopyranoside has inhibitory activity against the enzyme yeast a-glucosidase, withthe IC50 value of 287.12 muM.

4-Nitrophenyl β-D-mannopyranoside serves as a valuable substrate for β-D-mannopyranosidase. Additionally, it acts as a substrate for GH1-glucosidase (EaBgl1A) and α-L-rhamnosidase.

6-Chloro-1H-indol-3-yl β-D-glucopyranoside can be used as a chromogenic medium for detecting yeast with β-glucosidase activity.

D-Glucopyranose, 98% (α-Sophorose, 98%) serves as a substrate for various glycoside hydrolases, including α-glucosidase, and is also utilized in the study of glycobiology.