a-conotoxin mii

α-Conotoxin MII is a highly potent and selective competitive antagonist for α3β2 subunit-containing nicotinic receptors (IC50 = 0.5 - 3.5 nM at α3β2 expressed in Xenopus oocytes). Also potently blocks β3-containing neuronal nicotinic receptors. Displays >

α-Conotoxin MII acetate is a 16-amino acid peptide from the venom of the marine snail Conus magus. α-Conotoxin MII acetate potently blocks nicotinic acetylcholine receptors composed of α3β2 subunits, with an IC50 of 0.5 nM. α-Conotoxin MII acetate potently blocks β3-containing neuronal nicotinic acetylcholine receptors.

AT-1001 (Larazotide) is an orally active tight junction regulator and Zonulin antagonist. It reduces intestinal permeability in celiac and inflammatory bowel disease models by blocking Zonulin receptor signaling to maintain the integrity of epithelial tight junctions.

α-Conotoxin MII TFA (α-CTxMII TFA), a peptide of 16 amino acids derived from Conus magus venom, selectively inhibits nicotinic acetylcholine receptors (nAChRs) composed of α3β2 subunits with an IC50 of 0.5 nM and effectively targets β3-containing neuronal nicotinic receptors. [1] [2] [3]