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(3)
By Target- Akt
- CDK(3)
- ERK(3)
- PKA(3)
- PKC(2)
- GSK-3(1)
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Results for "
a 674563
" in TargetMol Product Catalog- Inhibitors & Agonists3
a-674563
A674563
T6139552325-73-2
A-674563 is an Akt1 inhibitor with Ki of 11 nM, modest potent to PKA and >30-fold selective for Akt1 over PKC.
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A-674563 2HCl(552325-73-2(fb-2hcl))
T6139L
A-674563 2HCl is an Akt1 inhibitor with Ki of 11 nM, modest potent to PKA and >30-fold selective for Akt1 over PKC.
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A-674563 HCl (552325-73-2(free base))
T44442070009-66-2
A-674563 is an orally available, ATP-competitive, and reversible inhibitor of Akt (Ki: 11 nM for Akt1) [1]. It exhibits inhibitory activity against PKA and Cdk2 (IC50: 16 46 nM) but is 10- to >1, 800-fold selective for Akt1 versus additional kinases in th
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