T8259

Doxycycline monohydrate is an inhibitor of metalloproteinase (MMP)

Decanoyl-Arg-Val-Arg-Lys-chloromethylketone (DEC-RVRK-CMK) is a small, synthetic, irreversible cell-permeable competitive inhibitor of furin that exhibits strong antiviral activity against Zika virus (ZIKV) and Japanese encephalitis virus (JEV) [1].

"Debotansine, an immunomodulator and antineoplastic [1], is a chemical compound with therapeutic applications in modulating the immune system and combating cancer."

DEALA-Hyp-YIPD, an HIF-1α peptide inhibitor, impedes the VHL/HIF-1α interaction with an half-maximal inhibitory concentration (IC50) of 0.91 μM and a dissociation constant (Kd) of 180 nM [1].

Deac-SS-Biotin, a potent antitumor compound, enters cells via biotin-mediated internalization and, when combined with DTT (Glutathione mimetic), effectively inhibits microtubule assembly, exhibiting enhanced antitumor activity [1].

Compound 5, DDC 3′-O-β-D-glucuronide, is a drug metabolite with properties that inhibit the fibrillization and oligomerization of Aβ42, suggesting its potential utility in Alzheimer's disease research [1].