T8236

RHC 80267 (U-57908) is a selective inhibitor of DAGL, with an IC50 of 4 μM in canine platelets.

FXIIa-IN-1 HCl (Compound 22) is a highly efficient and selective inhibitor of Factor XIIa, with a Ki app value of 97.8 nM, and can be used to study thrombosis and inflammation induced by artificial surfaces.

XIIa-IN-1-IN-2 (Compound 21) serves as a potent Factor XIIa inhibitor with an apparent inhibition constant (K i app) of 62.2 nM, utilized primarily in thrombosis research [1].

XIIa-IN-1-IN-3 (Compound 22) is a Factor XIIa inhibitor with a K i app of 97.8 nM, used in thrombosis research [1].

Furanogermacra-1(10)Z,4Z-dien-6-one, a furanosesquiterpenoid, is found in Commiphora myrrha [1].

Fulvotomentoside B is a natural saponin discovered in Lactobacillus flavus, suitable for biochemical experiments and medicinal synthesis research.

Fulvestrant 3-β-D-Glucuronide, a glucuronide and sulfate conjugate metabolite of the pure anti-estrogenic steroid Fulvestrant, is utilized in breast cancer research [1].

Fulranumab (AMG-403) is a humanised monoclonal antibody targeting nerve growth factor (NGF), which blocks the binding and activation of NGF with TrkA and p75NTR and has analgesic effects, and can be used for the study of chronic pain.

FTO-IN-10 (compound 7), a potent inhibitor of the human demethylase FTO (fat mass and obesity-associated protein), exhibits an IC50 of 4.5 μM. It interacts with the binding pocket of FTO's structural domain II via hydrophobic and hydrogen bonding interactions, and promotes DNA damage and autophagic cell death in A549 cells [1].