T3888

Scopolin (Scopoloside) formation is increased by the enhanced activity of PAL. Scopolin can reduce the clinical symptoms of rat AIA by inhibiting inflammation and angiogenesis, and this compound may be a potent agent for angiogenesis related diseases and can serve as a structural base for screening more potent synthetic analogs.

Thailanstatin A is an ultra-potent inhibitor of eukaryotic RNA splicing (IC50 = 650 nM). It inhibits multiple cancer cell lines via non-covalent binding to the SF3b subunit of the U2 snRNA subcomplex of the spliceosome, displaying low-nM to sub-nM IC50s. Thailanstatin A, as a payload for ADCs, is conjugated to the lysines on trastuzumab, yielding linker-less ADC.

Antibacterial agent 55 [example 21] is an antibacterial agent.

Antibacterial agent 56 (example 22) is an antibacterial agent.

Antibacterial Agent 58 (AA58) is a potent antibacterial compound that effectively reduces the minimum inhibitory concentration (MIC) value of Ceftazidime, another antibacterial agent.

Antibacterial agent 59 (example 24) is an antibacterial compound.

Antibacterial agent 57 (example 25) is an antibacterial agent.

Antibacterial agent 60 is a potent compound that effectively reduces the minimum inhibitory concentration (MIC) of Ceftazidime, an antibacterial agent.

Antibacterial agent 61 (example 27) is an antibacterial compound.

TRAP-6 amide TFA is a thrombin receptor agonist peptide targeting PAR-1.

Azide-PEG3-Desthiobiotin is a PROTAC linker belonging to the PEG class and can be used to synthesize PROTAC molecules.