T1929

Filgotinib (GLPG0634) is a selective JAK1 inhibitor with IC50 values of 10 nM for JAK1, 28 nM for JAK2, 810 nM for JAK3, and 116 nM for TYK2.

DL-Lysine is a racemic mixture of the D- and L-isomers of lysine. It is a synthetic form of the essential amino acid lysine and is used in cell culture, as a feed additive, and in biochemical research. The L-form participates in protein synthesis, while the D-form is used in certain metabolic studies to investigate amino acid transport and metabolic pathways.

DL-threo-2-methylisocitrate is a substrate of isocitrate lyase 1 (ICL1). Using Michaelis-Menten nonlinear least squares fitting, the kcat value was 1.25 s-1 and the Km was 718 μM. In comparison, the Km of threonine-D(s)L(s)-isocitrate (ICA) was 188 μM and the kcat was 5.24 s-1.

dl-threo-2-methylisocitrate is a substrate of isocitrate lyase 1 (ICL1). IC50 value: target: using michael-menten nonlinear least squares fitting to determine the purified recombinant ICL1's Km for threo-D(s)L(s)-isocitrate (ICA) is 188°M and kcat is 5.24

Docosahexaenoic Acid methyl ester (all cis-DHA methyl ester) is a methylated docosahexaenoic acid analog that can be inserted into membrane phospholipids without being oxidized or hydrolyzed.

Docosapentaenoic acid 22n-3 is present in the cell membranes of all animals and is a component of phospholipids.

DOTA derivatives are phenoxy derivatives of cyclic Tosamide;Direct nitrification;It is more convenient to add nitro group after removing the protection of lithium aluminium hydride.

Doxazosin-D8 is a deuterium labeled Doxazosin (T22316) (UK 33274).Doxazosin, a quinazoline derivative, selectively antagonizes postsynaptic AP1 adrenergic receptor.

DTE (Dithioerythritol) is a sulfur-containing sugar derivative of the four-carbon monosaccharide erythrose and is an epimer of dithiothreitol (DTT), Dithioerythritol (DTE) is commonly used as a reducing agent in biochemical and molecular biology experiments to maintain thiol groups in a reduced state, stabilize protein structure, and support redox-sensitive enzymatic and structural studies.