T1605

Enalapril is a dicarbocyl-containing peptide and angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.

Methylamino-PEG2-Boc is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules [PROTACs]. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Methylamino-PEG3-azide is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules, and enabling selective protein degradation through the ubiquitin-proteasome system within cells.

Methylamino-PEG4-acid is a PEG-based linker for PROTACs, joining two essential ligands critical for PROTAC molecule formation, and enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Methylamino-PEG4-Boc is a PEG-based linker for PROTACs, facilitating the conjugation of two essential ligands critical for producing PROTAC molecules, thereby enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Methylamino-PEG5-azide is a PEG-based linker for PROTACs that connects two essential ligands critical for forming PROTAC molecules, enabling selective protein degradation through the ubiquitin-proteasome system within cells.

Methyltetrazine-acid is an alkyl chain-derived linker used for PROTAC synthesis [1].

Methyltetrazine-DBCO is a non-cleavable linker used in the synthesis of antibody-drug conjugates (ADCs) [1].

Methyltetrazine-PEG4-amine is a polyethylene glycol (PEG) derivative serving as a PROTAC linker for the synthesis of PROTACs[1].

Methyltetrazine-PEG4-maleimide is a PEG-based PROTAC linker that synthesises PROTAC molecules. Methyltetrazine-PEG4-maleimide contains a Tetrazine moiety and can undergo an iEDDA click with molecules containing a TCO moiety.

Methyltetrazine-PEG5-alkyne, a PEG-based PROTAC linker, is utilized in synthesizing PROTACs[1].

Enalapril sodium is used to treat high blood pressure, diabetic kidney disease, and heart failure and can be generally used with a diuretic such as furosemide for heart failure.