T1068

Dithranol (cignoline) is an anthracene derivative that disrupts MITOCHONDRIA function and structure and is used for the treatment of DERMATOSES, especially PSORIASIS. It may cause FOLLICULITIS.

Carmoxirole hydrochloride (EMD 45609 hydrochloride) is a selective dopamine D2 receptor agonist with in vivo antihypertensive activity.

Casein Kinase II Inhibitor IV is an inducer of epidermal keratinocyte differentiation.

Carebastine, the active metabolite of Ebastine, is an antagonist of the histamine H1 receptor.

Cariprazine-D6 is a deuterium-labeled Cariprazine. Cariprazine (T4577) is an antipsychotic agent (D3 receptors, Ki: 0.085 nM; D2 receptors, Ki: 0.49 nM).

CARM1-IN-1 (CARM1-IN-7G) is a selective inhibitor of CARM1 with IC50 of 8.6 μM. CARM1-IN-1 shows weak activity against PRMT1 and SET7 with IC50 > 600 μM.

Carnostatine (SAN9812) is a potent and selective carnosinase 1 (CN1) inhibitor with a K_i of 11 nM for human recombinant CN1. It may be used to increase renal carnosine concentration as a potential therapeutic modality for diabetic nephropathy (DN). [1].

Carnostatine hydrochloride (SAN9812 hydrochloride) is a potent and selective inhibitor of carnosinase 1 (CN1), with a K_i of 11 nM against human recombinant CN1, showing promise for the treatment of diabetic nephropathy (DN) [1].

Carpaine is a natural product exhibiting antimalarial activity, with an approximate IC50 of 4μM against P. falciparum in NL20 cells. It demonstrates cardioprotective and anti-inflammatory effects by activating FAK, ERK1/2, and AKT pathways while inhibiting ROS production.

4-Hydroxyphenyl Carvedilol, a metabolite of Carvedilol, is associated with the pharmacological activity of this beta-blocker/alpha-1 blocker.

Casein Kinase II Inhibitor IV Hydrochloride is a small-molecule inducer of epidermal keratinocyte differentiation, offering novel therapeutic approaches for treating skin hyperproliferative disorders.

Casopitant mesylate (GW679769B) is a selective, brain-permeable, and orally active antagonist of the neurokinin 1 (NK1) receptor, and it is the second in its class of antiemetics.

Cauloside D, a triterpene glycoside isolated from Caulophyllum robustum Max, inhibits the expression of iNOS and proinflammatory cytokines with anti-inflammatory effects.