T0455

Clozapine (HF 1854) is a tricylic dibenzodiazepine, classified as an atypical antipsychotic agent. It binds several types of central nervous system receptors, and displays a unique pharmacological profile. Clozapine is a serotonin antagonist, with strong binding to 5-HT 2A/2C receptor subtype. It also displays strong affinity to several dopaminergic receptors, but shows only weak antagonism at the dopamine D2 receptor, a receptor commonly thought to modulate neuroleptic activity.

Hexanal-2,4-dinitrophenylhydrazone-d12 (Hexanal-DNPH-d12) is the deuterium-labeled version of 1-(2,4-Dinitrophenyl)-2-hexylidenehydrazine.

Clozapine-D3 is a deuterated compound of Clozapine. Clozapine (T0455) has a CAS number of 5786-21-0. Clozapine (T0455) is a tricylic dibenzodiazepine, classified as an atypical antipsychotic agent. It binds several types of central nervous system receptors, and displays a unique pharmacological profile. Clozapine (T0455) is a serotonin antagonist, with strong binding to 5-HT 2A/2C receptor subtype. It also displays strong affinity to several dopaminergic receptors, but shows only weak antagonism at the dopamine D2 receptor, a receptor commonly thought to modulate neuroleptic activity.