T0112

Diltiazem hydrochloride (RG 83606 HCl) is a benzothiazepine calcium channel blocking agent with vasodilating action due to its antagonism of the actions of CALCIUM ion on membrane functions.

Diltiazem (CRD 401 free base) is an orally available L-type Ca2+ channel blocker with antihypertensive, antiarrhythmic, and cardioprotective properties that prevent post-reperfusion myocardial injury, angina pectoris, and cardiovascular-related diseases.

Diltiazem malate is an ACE inhibitor and non-dihydropyridine calcium channel blocker used in the treatment of hypertension.

Urea-13C,15N is a form of urea labeled with 13C and 13N. Urea functions as a potent protein denaturant through direct and indirect mechanisms. It acts as an effective emollient and keratolytic agent and is also utilized as a diuretic. Blood urea nitrogen (BUN) levels are employed to assess kidney function. Urea is widely used as a nitrogen source in fertilizers and serves as a vital raw material in the chemical industry.