elestat — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T6488	Epinastine hydrochloride	Alesion,Epinastine HCl,WAL-801CL HCl,Elestat	5-HT Receptor , Histamine Receptor
	Epinastine hydrochloride (WAL-801CL HCl) is an antihistamine and mast cell stabilizer that is used in eye drops to treat allergic conjunctivitis.		5-HT Receptor , Histamine Receptor
T3107	Alvelestat	AZD9668,Avelestat	Others , Serine Protease
	Alvelestat (AZD9668) is an orally bioavailable, selective and reversible inhibitor of human neutrophil elastase (NE), with potential anti-inflammatory activity.		Others , Serine Protease
T20762	Sivelestat sodium tetrahydrate	ONO-5046 sodium tetrahydrate,Elaspol,ONO 5046,ONO5046 sodium tetrahydrate,Elaspol sodium tetrahydrate,ONO-5046,Sivelestat Sodium,Sivelestat Sodium Hydrate,ONO5046	Serine Protease
	Sivelestat sodium tetrahydrate (ONO5046 sodium tetrahydrate) is a competitive inhibitor of human neutrophil elastase, with an IC50 of 44 nM and a Ki of 200 nM. Sivelestat (EI546) sodium tetrahydrate has the potential for...		Serine Protease
T6986	Sivelestat	ONO5046,EI546,LY544349	Others , SARS-CoV , Serine Protease
	Sivelestat (ONO5046) is a potent and selective inhibitor of neutrophil elastase with IC50 of 44 nM.		Others , SARS-CoV , Serine Protease
T31877	Freselestat	ONO-PO 736,ONO-6818,ONO 6818,ONO6818
	Freselestat (ONO-6818) is a potent neutrophil elastase inhibitor that significantly reduces the production of interleukin 8 and C5B-9. Freselestat reduces inflammatory mediators during simulated cardiopulmonary bypass.
T73657	Tiprelestat
	Tiprelestat, a potent inhibitor of human neutrophil elastase, exhibits antimicrobial and anti-inflammatory properties. It is utilized in the study of inflammation and immune diseases [1].
T62846	Freselestat quarterhydrate
	Freselestat quarterhydrate (ONO-6818 quarterhydrate) is a potent, orally active inhibitor of neutrophil elastase (Ki: 12.2 nM). quarterhydrate is more than 100-fold less active than other proteases such as trypsin, prote...
T3107L	Alvelestat tosylate
	Alvelestat can inhibit neutrophil elastase (NE), which acts an important role in NET formation.
T41043	Lonodelestat	POL6014
	Lonodelestat (POL6014) is a potent, orally active and selective peptide inhibitor of human neutrophil elastase (hNE).
T76216	Lonodelestat TFA
	Lonodelestat TFA (POL6014 TFA) is a potent, selective peptide inhibitor of human neutrophil elastase (hNE), demonstrating oral activity. It holds promise for cystic fibrosis (CF) research [1] [2] [3].
T21414	Sivelestat sodium	ONO 5046,LY-544349,Sivelestat sodium salt,ONO-5046,ONO5046,LY544349,LY 544349
	Sivelestat, an inhibitor of human neutrophil elastase, is used in the treatment of acute respiratory failure. Preliminary studies show Sivelestat may improve neuropathic pain.