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4,9anhydrotetrodotoxin

" in TargetMol Product Catalog
  • Inhibitors & Agonists
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    TargetMol | All_Pathways
4,9-Anhydrotetrodotoxin
4,9-anhydro-TTX, 4,9-Anhydrotetrodotoxin
T3709313072-89-4
4,9-Anhydrotetrodotoxin (4,9-anhydro-TTX) is a derivative of TTX that selectively blocks inward sodium current through Nav1.6 voltage-activated sodium channels (IC50 = 7.8 nM in Xenopus oocytes). [1][2][3] It demonstrates IC50 values of 1.3, 0.34, 0.99, 78.5, 1.3, and >30 µM for Nav1.2, Nav1.3, Nav1.4, Nav1.5, Nav1.7, and Nav1.8, respectively.[1]
  • $858
35 days
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