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Results for "
2641998-63-0
" in TargetMol Product Catalog- Inhibitors & Agonists1
RMC6291, RMC 6291, 2775304-30-6
T751312641998-63-0
RMC-6291 is an orally active, covalent inhibitor of KRAS G12C (ON) that forms a tri-complex within tumor cells between KRAS G12C (ON) and cyclophilin A (CypA), thereby preventing KRAS G12C (ON) from signaling via steric blockade of RAS effector binding and eliciting deep and durable suppression of RAS pathway activity in KRAS G12C tumor models [1].
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