Polygalacin D shows anti- proliferation, anti-inflammary, and hepatoprotective activities, it can inhibit the expression of lipopolysaccharide (LPS)-induced iNOS and COX-2 protein and mRNA without an appreciable cytotoxic effect on RAW 264.7 macrophages, and can suppress induction by LPS of pro-inflammatory cytokines such as prostaglandin E2 (PGE2).

Polygalasaponin F has anti-neuroinflammatory activity, can inhibit the release of inflammatory cytokines TNF-α and NO induced by lipopolysaccharides (LPS) and reduce the expression of inducible nitric oxide synthases. Polygalasaponin F can significantly i

Euxanthone (1,7-Dihydroxyxanthone), an xanthone derivative extracted from the roots of Polygala tenuifolia Willd, has antitumour, neuroprotective and vasorelaxant activities, and attenuates Aβ1-42-induced oxidative stress and apoptosis by inducing autophagy.SB-674042 is used for the treatment of depression.SB-674042 is used for the treatment of depression.SB-674043 is used for the treatment of depression.SB-674044 is used for the treatment of depression.SB-674045 is used for the treatment of depression. 2A (BU-1) cell differentiation.

Tenuifoliose A is a natural product from Polygala tenuifolia Willd.

Lancerin, extracted from the root bark of Cudrania cochinchinensis, exhibits antioxidative activity against lipid peroxidation.

Polygalacic acid (Virgaureagenin G) is a triterpenoid isolated from the root of Polygala tenuifolia Willd that inhibits MMP expression. Polygalacic acid (Virgaureagenin G) can significantly improve the responsiveness of the cholinergic system, such as decreased acetylcholinesterase (AChE) activity, increased choline acetyltransferase (ChAT) activity, and increased acetylcholine (ACh) levels in the hippocampus and frontal cortex. Polygalacic acid (Virgaureagenin G) can also inhibit IL-1β-induced Wnt β-catenin activation and mitogen-activated protein kinase (MAPK) signaling pathways in chondrocytes, and is used in osteoarthritis (OA) related research.

Sibiricose A1 is a natural product for research related to life sciences. The catalog number is TN5016 and the CAS number is 139726-40-2.

7-Z-Trifostigmanoside I is a natural product from Polygala hongkongensis Hemsl.

Polygalasaponin XXXV is a natural product for research related to life sciences. The catalog number is TN6533 and the CAS number is 184479-28-5.

Polygalasaponin XLIX is a natural product for research related to life sciences. The catalog number is TN6532 and the CAS number is 1033593-12-2.

Sibiricaxanthone A (Sibiricaxanthone A) is a natural product from Polygala tenuifolia

1,7-Dihydroxy-2,3-methylenedioxyxanthone exhibits antiulcerogenic, anti-oxidation, and antihyperalgesic activities and can inhibit carrageenan-induced hyperalgesia.

4-Hydroxyvertixanthone is a natural product for research related to life sciences. The catalog number is TN4522 and the CAS number is 85003-85-6.

Arillanin A is a natural product from Polygala tenuifolia Willd.

Polygalasaponin E is a natural product for research related to life sciences. The catalog number is TN6531 and the CAS number is 882664-72-4.

1,7-Dimethoxy-2,3-methylenedioxyxanthone is a natural product for research related to life sciences. The catalog number is TN2521 and the CAS number is 145523-71-3.

1,7-Dihydroxy-2,3-dimethoxyxanthone may have medicinal use in managing inflammation, asthma, and allergy; it non-competitively but reversibly antagonizes contractions induced by chemical inflammatory mediators in the guinea pig trachea in vitro and significantly inhibits LPS-induced NO production in BV2 microglia cells.

6-Hydroxy-1,2,3,7-tetramethoxyxanthone is a natural product from Polygala sibirica L.

Onjisaponin Z is a natural product known as a triterpenoid saponin, characterized by its molecular structure that includes a sapogenin (aglycone) attached to one or more sugar moieties. Commonly found in the root of the medicinal herb Polygala tenuifolia, Onjisaponin Z exhibits a range of pharmacological effects, such as neuroprotective, anti-inflammatory, and antioxidant activities.

Bayogenin 3-O-beta-D-glucopyranoside is a natural product from Polygala japonica Houtt.

Tenuifoliose J is a natural product from Polygala tenuifolia Willd

Polygalin C is a natural product for research related to life sciences. The catalog number is TN6529 and the CAS number is 934768-05-5.

Arganine B is a natural product for research related to life sciences. The catalog number is TN6438 and the CAS number is 144425-21-8.

Polygalacin D2 may have antimicrobial activity.