Gambogic Acid (Guttic Acid) ( EC50=0.78-1.64 uM) activates caspases. Gambogic Acid competitively suppresses Bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 and Mcl-1. The IC50s of Gambogic Acid for Bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 and Mcl-1 are 1.47, 1.21, 2.02, 0.66, 1.06 and 0.79 uM, respectively.

Gambogenic acid is a natural product,is an effective inhibitor of EZH2,with anticancer activity.

GB 2a shows antioxidant and anti-inflammatory effects, it can prevent the carrageenan-induced paw oedema. GB 2a biflavonoid can promote inhibition on tyrosinase activity and reduced melanin biosynthesis in B16F10 cells, which suggests great potential for

Subelliptenone G is a natural product from Garcinia hanburyi Hook.f.

Isogambogic acid shows cytotoxic activiity against KB and drug-resistant KB-V1 cell lines.

Mangostanol is an acetylcholinesterase (AChE) selective inhibitor.Mangostanol has anti-cancer activity, it shows significant activities against the CEM-SS cell line, with IC50 values of 9.6 microg/ml.

Garcinone E is active constituents in the anticomplement assay used. Garcinone E exhibits potent activity in vitro against Plasmodium falciparum chloroquine-resistant strain W2, with IC50 values below 3 µM. It has potent cytotoxic effect on all hepatocellular carcinomas cell lines as well as on the other gastric and lung cancer cell lines included in the screen, may be potentially useful for the treatment of certain types of cancer.

Isomorellic acid is a cytotoxic caged xanthone.

7-Prenyljacareubin shows moderate cytotoxic activity against HL-60, SMMC-7721, A549, MCF-7, and SW480 cell lines.

1,6,7-Trihydroxyxanthone has anti-cancer activity ,at least in part, through the activation of miR-218 and suppression of Bmi-1 expression; can suppress cell growth and induce apoptosis in liver cancer cells.

Parvifolixanthone A is a natural product from Garcinia parvifolia.

2,5-Dihydroxyxanthone is a natural product for research related to life sciences. The catalog number is TN2731 and the CAS number is 35040-32-5.

Parvifolixanthone B is a natural product from Garcinia parvifolia.

1,4,6-Trihydroxy-5-methoxy-7-prenylxanthone is a natural product for research related to life sciences. The catalog number is TN2494 and the CAS number is 160623-47-2.

Isogarciniaxanthone E is a natural product from Garcinia mangostana.

1,4,5,6-Tetrahydroxy-7-prenylxanthone has anti-cancer activity, it shows moderate cytotoxicities against breast cancer (MDA-MB-435S) and lung adenocarcinoma (A549) cell lines; it also exhibits moderate activities with GI50 (Growth inhibitory) values of 2.

Isonormangostin is a natural product of Garcinia, Clusiaceae. The catalog number is TN4316 and the CAS number is 15404-80-5. Isonormangostin can be used as a reference standard.

1,5,6-Trihydroxyxanthone exhibits antibacterial activity against Gram-positive bacteria.

9-Hydroxycalabaxanthone exhibits cytotoxicity against the HT-29 cell line with ED50 values of 9.1 microM. The combination of 9-hydroxycalabaxanthone with α±-mangostin shows the synergistic antimalarial interaction in both clones.

1,4,5,6-Tetrahydroxy-7,8-diprenylxanthone has moderate cytotoxicities against breast cancer (MDA-MB-435S) and lung adenocarcinoma (A549) cell lines, but lacks antifungal activity against Candida albicans.

Griffipavixanthone inhibits the growth of human Non-small-cell lung cancer H520 cells in dose- and time-dependent manners, it induces cell apoptosis through mitochondrial apoptotic pathway accompanying with ROS production. It can inhibit tumor metastasis

Isojacareubin displays potent activity against H. pylori HP40 clinical isolate with MIC 23.9 uM, which is approximately two times greater than that of the standard drug amoxicillin. Isojacareubin is a potent inhibitor of protein kinase C (PKC), suppresses

1,5,8-Trihydroxy-3-methoxy-2-prenylxanthone is a natural product for research related to life sciences. The catalog number is TN2503 and the CAS number is 110187-11-6.

1,5-Dihydroxyxanthone exhibits the epidermal growth factor receptor (EGFR) -tyrosine kinase inhibitory activity, with the IC50 value of 90.34 nM. It may have anticholinesterase activity on acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) enzym

The synthetic caged Garcinia xanthone cluvenone induces cell stress and apoptosis and has immune modulatory activity.

BR-Xanthone A is a natural product for research related to life sciences. The catalog number is TN3535 and the CAS number is 112649-48-6.

Beta-Tocotrienol to serve as a new anticancer agent for treating human lung and brain cancers. It inhibits the growth of both A549 (GI50=1.38±0.334μM) and U87MG (GI50=2.53±0.604μM) cells at rather low concentrations.

1,5,6-Trihydroxy-3,7-dimethoxyxanthone shows cytotoxic activity against the KB cell line.

1-Isomangostin has cytotoxic and anticomplementary activities.

2,3',4,6-Tetrahydroxybenzophenone possesses significant antioxidant activity.

alpha-Mangostin (Mangostin) is a natural xanthonoid, a type of organic compound isolated from various parts of the mangosteen tree.

3-Isomangostin is a potent human aldose reductase inhibitor with an IC50 of 3.48 uM; it is also an acetylcholinesterase selective inhibitor. 3-Isomangostin has free radical scavenging activity; it shows antiplasmodial activity with IC50 values in the rang

Neogambogic acid, an active ingredient in garcinia, can inhibit the growth of some solid tumors and result in an anticancer effect, it may be responsible for the inhibition of proliferation of human breast cancer cell line MCF-7 cells.

3-(3-Hydroxy-3-methylbutanyl)-2,4,6-trihydroxybenzophenone is a natural product for research related to life sciences. The catalog number is TN2862 and the CAS number is 1432062-53-7.

6-Prenylapigenin(4',5,7-Trihydroxy-6-prenylflavone) shows potent inhibitory activity on melanin formation, it may be potential sources for skin whitening agents. It also shows moderate cytotoxicities against breast cancer (MDA-MB-435S) and lung adenocarci

8-Benzoyl-5,7-dihydroxy-2,2-dimethylchromane is a natural product for research related to life sciences. The catalog number is TN3272 and the CAS number is 63565-07-1.

O-Demethylforbexanthone is a natural product for research related to life sciences. The catalog number is TN4686 and the CAS number is 92609-77-3.

6-Benzoyl-5,7-dihydroxy-2,2-dimethylchromane is a natural product for research related to life sciences. The catalog number is TN3154 and the CAS number is 86606-14-6.

Nigrolineaxanthone V is a natural product of Garcinia, Clusiaceae. The catalog number is TN4657 and the CAS number is 864516-31-4. Nigrolineaxanthone V can be used as a reference standard.

Garcinexanthone A is a natural product for research related to life sciences. The catalog number is TN4111 and the CAS number is 1107620-67-6.

2,4'-Dihydroxybenzophenone can effectively protect C57BL/6J mice from APAP-induced hepatotoxicity. Its mechanisms might be associated with its Antioxidant activity.

Latisxanthone C shows inhibitory effects on Epstein-Barr virus early antigen (EBV-EA) activation induced by 12-O-tetradecanoylphorbol-13-acetate (TPA) in Raji cells, it may be a valuable antitumor promoter.

1,7-Dihydroxy-3-methoxy-2-prenylxanthone is a natural product for research related to life sciences. The catalog number is TN2518 and the CAS number is 77741-58-3.

2,2',3'-Trihydroxy-4,6-dimethoxybenzophenone is a natural product for research related to life sciences. The catalog number is TN2677 and the CAS number is 219861-73-1.

Garcinone C is a xanthone derivative extracted from Garcinia oblongifolia Champ with anti-inflammatory, astringency, and granulation-promoting activities. Garcinone C is an AChE inhibitor and has potential cytotoxic effects on certain cancers.

Gartanin is an androgen receptor degradation enhancer, it is also a potential neuroprotective agent against glutamate-induced oxidative injury partially through increasing Nrf-2-independed HO-1 and AMPK SIRT1 PGC-1α±signaling pathways.

Beta-mangostin (β-Mangostin) is a xanthone compound with antibacterial and antimalarial activities. Beta-mangostin present in Cratoxylum arborescens and exhibits antimycobacterial activity against Mycobacterium tuberculosis with an MIC of 6.25 μg mL. Beta-mangostin possesses in vitro antimalarial activity against Plasmodium falciparum, with an IC50 of 3.00 μg mL. Beta-mangostin has potent anticancer activity against various cancers (such as hepatocellular carcinoma, leukaemic).

Paucinervin A has inhibitory effect against HeLa cell growth, with the IC50 value of 29.5 microM.

(-)-Hydroxycitric acid (HCA) can inhibit fat synthesis and reduces food intake, the primary mechanism of action of HCA appears to be related to its ability to act as a competitive inhibitor of the enzyme ATP-citrate lyase, which catalyzes the conversion of citrate and coenzyme A to oxaloacetate and acetyl coenzyme A (acetyl-CoA), primary building blocks of fatty acid and cholesterol synthesis.

3-Isomangostin hydrate is a natural product for research related to life sciences. The catalog number is TN2954 and the CAS number is 26063-96-7.