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Tyrosinase

Tyrosinase is a copper-containing enzyme present in plant and animal tissues that catalyzes the production of melanin and other pigments from tyrosine by oxidation. It is found inside melanosomes which are synthesised in the skin melanocytes.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T5552 Methyl cinnamate 103-26-4 99.95%
Methyl cinnamate
Methyl cinnamate, a tyrosinase inhibitor and a flavoring compound, has antimicrobial, antiadipogenic, vasorelaxant, and anti-inflammatory effects.
T6463 Deoxyarbutin 53936-56-4 99.94%
Deoxyarbutin
DeoxyArbutin(IC50=50 nM) inhibits tyrosinase activity reversibly.
TCS2170 2,5-Dihydroxyacetophenone 490-78-8 99.91%
2,5-Dihydroxyacetophenone
1. 2,5-Dihydroxyacetophenone (Quinacetophenone) possess anti-anxiety, and neuroprotective qualities. 2. 2,5-Dihydroxyacetophenone (Quinacetophenone) reatment can...
T8087 Tropolone 533-75-5 99.89%
Tropolone
Tropolone, a metal chelator, possesses weak antioxidative and radical-scavenging properties and shows a strong affinity for ferric ion
T2742 Aloin 1415-73-2 99.89%
Aloin
Aloin (Aloin-A)(mixture of A&B), a natural anthracycline from Aloe vera, is a tyrosinase inhibitor.
TCS1709 BENZYLACETONE 2550-26-7 99.87%
BENZYLACETONE
Benzylacetone (4-Phenyl-2-butanone) is an aromatic compound extracted from incense wood. Benzylacetone has appetite-enhancing and exercise-reducing properties. B...
T15753 Licraside 29913-71-1 99.85%
Licraside
Licraside is a tyrosinase inhibitor with an IC50 of 0.072 mM for monophenolase and can be used in studies about antibrowning and depigmenting agents.
TN2246 Swertiajaponin 6980-25-2 99.83%
Swertiajaponin
Swertiajaponin possesses antimicrobial activity.
TN1545 D-Tyrosine 556-02-5 99.82%
D-Tyrosine
D-Tyrosine, the D-isomer of tyrosine, acts as a negative regulator of melanin synthesis by inhibiting tyrosinase activity. Furthermore, D-Tyrosine also inhibits ...
T7966 3-O-Ethyl-L-ascorbic acid 86404-04-8 99.8%
3-O-Ethyl-L-ascorbic acid
3-O-Ethyl-L-ascorbic acid is a cosmetic tyrosinase inhibitor with whitening ability and is a stabilized vitamin C derivative. It also has antioxidant properties....
T0314 Hexylresorcinol 136-77-6 99.72%
Hexylresorcinol
Hexylresorcinol (4-Hexylresorcinol) is a substituted dihydroxybenzene used topically as an antiseptic for the treatment of minor skin infections.
T4291 (+)-Isocorydine hydrochloride 13552-72-2 99.72%
(+)-Isocorydine hydrochloride
(+)-Isocorydine hydrochloride (Isocorydine HCl) is a eukaryote protein kinases Inhibitor.
T3S1068 Oxyresveratrol 29700-22-9 99.69%
Oxyresveratrol
1. Oxyresveratro can inhibit tyrosinase activity. 2. Oxyresveratro is useful to trauma models, as toxicity to glia could be beneficial by inhibiting reactive gli...
T0759 Monobenzone 103-16-2 99.69%
Monobenzone
Monobenzone (Benoquin) is a Depigmenting Agent. The mechanism of action of monobenzone is as a Melanin Synthesis Inhibitor. The physiologic effect of monobenzone...
T2A2524 2-Hydroxy-4-methoxybenzaldehyde 673-22-3 99.64%
2-Hydroxy-4-methoxybenzaldehyde
2-Hydroxy-4-methoxybenzaldehyde (4-Methoxysalicylaldehyde) is a chemical compound and an isomer of Vanillin. 2-Hydroxy-4-methoxybenzaldehyde(4-Methoxysalicylalde...
T77649 HTYR/AbTYR-IN-1 1625821-37-5 99.59%
hTYR/AbTYR-IN-1
hTYR/AbTYR-IN-1 is a dual hTYR/AbTYR inhibitor with inhibitory effects on hTYR and AbTYR, with IC50s of 5.4 μM and 3.52 μM, respectively. hTYR/AbTYR-IN-1 can be ...
T5755 Aloesin 30861-27-9 99.58%
Aloesin
Aloesin is a C-glycosylated chromone compound found in aloe (Liliaceae) that inhibits tyrosinase (IC50 = 0.9 mM), an enzyme responsible for catalyzing the first ...
T2S0973 2-Methoxycinnamic acid 6099-03-2 99.57%
2-Methoxycinnamic acid
1. 2-Methoxycinnamic acid (o-Methoxycinnamic acid) can enhance inhibition of tyrosinase activity.
T2340 AC1NS4RE 1055412-47-9 99.53%
AC1NS4RE
It is a tyrosine kinase inhibitor.
T3734 3',4'-Dihydroxyacetophenone 1197-09-7 99.49%
3',4'-Dihydroxyacetophenone
3',4'-Dihydroxyacetophenone (Qingxintong) is an active constituent of Chinese medicine. It is platelet aggregation Inhibitor and also has anti-arrhythmia activit...
Methyl cinnamate
T5552
Methyl cinnamate, a tyrosinase inhibitor and a flavoring compound, has antimicrobial, antiadipogenic, vasorelaxant, and anti-inflammatory effects.
Deoxyarbutin
T6463
DeoxyArbutin(IC50=50 nM) inhibits tyrosinase activity reversibly.
2,5-Dihydroxyacetophenone
TCS2170
1. 2,5-Dihydroxyacetophenone (Quinacetophenone) possess anti-anxiety, and neuroprotective qualities. 2. 2,5-Dihydroxyacetophenone (Quinacetophenone) reatment can...
Tropolone
T8087
Tropolone, a metal chelator, possesses weak antioxidative and radical-scavenging properties and shows a strong affinity for ferric ion
Aloin
T2742
Aloin (Aloin-A)(mixture of A&B), a natural anthracycline from Aloe vera, is a tyrosinase inhibitor.
BENZYLACETONE
TCS1709
Benzylacetone (4-Phenyl-2-butanone) is an aromatic compound extracted from incense wood. Benzylacetone has appetite-enhancing and exercise-reducing properties. B...
Licraside
T15753
Licraside is a tyrosinase inhibitor with an IC50 of 0.072 mM for monophenolase and can be used in studies about antibrowning and depigmenting agents.
Swertiajaponin
TN2246
Swertiajaponin possesses antimicrobial activity.
D-Tyrosine
TN1545
D-Tyrosine, the D-isomer of tyrosine, acts as a negative regulator of melanin synthesis by inhibiting tyrosinase activity. Furthermore, D-Tyrosine also inhibits ...
3-O-Ethyl-L-ascorbic acid
T7966
3-O-Ethyl-L-ascorbic acid is a cosmetic tyrosinase inhibitor with whitening ability and is a stabilized vitamin C derivative. It also has antioxidant properties....
Hexylresorcinol
T0314
Hexylresorcinol (4-Hexylresorcinol) is a substituted dihydroxybenzene used topically as an antiseptic for the treatment of minor skin infections.
(+)-Isocorydine hydrochloride
T4291
(+)-Isocorydine hydrochloride (Isocorydine HCl) is a eukaryote protein kinases Inhibitor.
Oxyresveratrol
T3S1068
1. Oxyresveratro can inhibit tyrosinase activity. 2. Oxyresveratro is useful to trauma models, as toxicity to glia could be beneficial by inhibiting reactive gli...
Monobenzone
T0759
Monobenzone (Benoquin) is a Depigmenting Agent. The mechanism of action of monobenzone is as a Melanin Synthesis Inhibitor. The physiologic effect of monobenzone...
2-Hydroxy-4-methoxybenzaldehyde
T2A2524
2-Hydroxy-4-methoxybenzaldehyde (4-Methoxysalicylaldehyde) is a chemical compound and an isomer of Vanillin. 2-Hydroxy-4-methoxybenzaldehyde(4-Methoxysalicylalde...
hTYR/AbTYR-IN-1
T77649
hTYR/AbTYR-IN-1 is a dual hTYR/AbTYR inhibitor with inhibitory effects on hTYR and AbTYR, with IC50s of 5.4 μM and 3.52 μM, respectively. hTYR/AbTYR-IN-1 can be ...
Aloesin
T5755
Aloesin is a C-glycosylated chromone compound found in aloe (Liliaceae) that inhibits tyrosinase (IC50 = 0.9 mM), an enzyme responsible for catalyzing the first ...
2-Methoxycinnamic acid
T2S0973
1. 2-Methoxycinnamic acid (o-Methoxycinnamic acid) can enhance inhibition of tyrosinase activity.
AC1NS4RE
T2340
It is a tyrosine kinase inhibitor.
3',4'-Dihydroxyacetophenone
T3734
3',4'-Dihydroxyacetophenone (Qingxintong) is an active constituent of Chinese medicine. It is platelet aggregation Inhibitor and also has anti-arrhythmia activit...
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TargetMol