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ROS

Reactive oxygen species (ROS) are chemically reactive chemical species containing oxygen. Examples include peroxides, superoxide, hydroxyl radical, singlet oxygen, and alpha-oxygen. The reduction of molecular oxygen (O2) produces superoxide (•O−2), which is the precursor of most other reactive oxygen species.In a biological context, ROS are formed as a natural byproduct of the normal metabolism of oxygen and have important roles in cell signaling and homeostasis. However, during times of environmental stress (e.g., UV or heat exposure), ROS levels can increase dramatically.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T15433 GSK2795039 1415925-18-6 98.68%
GSK2795039
GSK2795039 inhibits reactive oxygen species (ROS) production and NADPH consumption. GSK2795039 decreases apoptosis. GSK2795039 is an inhibitor of NADPH oxidase 2...
T3374 Dihydrotanshinone I 87205-99-0 98.67%
Dihydrotanshinone I
Dihydrotanshinone I (DHTS) is a natural compound extracted from Salvia miltiorrhiza Bunge used for treating of cardiovascular diseases.
T77579 JC2-11 937820-89-8 98.6%
JC2-11
JC2-11 is an inhibitory compound for inflammation.JC2-11 inhibits the recruitment domain-containing proteins NLRC 4, atypical in melanoma 2 (AIM 2) and atypical ...
TN1916 Matairesinol 580-72-3 98.53%
Matairesinol
Matairesinol has radical and superoxide scavenging activities,; it also has anti-angiogenic activity by suppressing mROS signaling , can decrease hypoxia-inducib...
T2864 Lycopene 502-65-8 98.47%
Lycopene
Lycopene (ψ,ψ-Carotene) is a linear, unsaturated hydrocarbon carotenoid, the major red pigment in fruits such as tomatoes, pink grapefruit, apricots, red oranges...
T4957 Carnosic acid 3650-09-7 98.31%
Carnosic acid
Carnosic acid is a lipid absorption inhibitor, endowed with antioxidative, antimicrobial, photoprotective potential, and antiproliferative properties.
T77578 CHBO4 98991-32-3 98.14%
CHBO4
CHBO4 is an hMAO-B inhibitor that is potent, reversible, competitive and selective.The IC50 value of CHBO4 against hMAO-B in the CHBO assay was 0.031 μM, and the...
TN1372 Alpha-Amyrin 638-95-9 98.14%
Alpha-Amyrin
Alpha-Amyrin (alpha-Amyrine) is an inhibitor of trypsin and chymotrypsin with antineoplastic effects. alpha-Amyrin can be used in studies about acting as a hepat...
T36488 LYG-202 1175077-25-4 98.05%
LYG-202
LYG-202 is a novel flavonoid with piperazine substitution and antitumor effects in vivo and in vitro.LYG-202 induced apoptosis in MCF-7, MDA-MB-231, and MDA-MB-4...
TN1002 Blumeatin 118024-26-3 97.79%
Blumeatin
Blumeatin has antioxidant properties, free radical scavenging activity,and has xanthine oxidase (XO) inhibitory activity.
T11254 F-1 2244775-31-1 97.66%
F-1
F-1 is IC50s of 2.1 nM, 2.3 nM, 1.3 nM and 3.9 nM for ALKWT, ROS1WT, ALKL1196M and ALKG1202R, respectively. F-1 is a potent ALK and ROS1 dual inhibitor, suppress...
T72082 Compound T72082(SC) 298193-11-0 97.53%
Compound T72082(SC)
ROS-IN-1 is a mitochondrial ROS inhibitor that can be used to reduce oxidative stress or inhibit reactive oxygen species (ROS) production.
TN2126 Quercetin-3-O-glucose-6''-acetate 54542-51-7 97.48%
Quercetin-3-O-glucose-6''-acetate
Quercetin-3-O-glucose-6''-acetate (6"-O-Acetylisoquercitrin) is an inhibitor of NADPH oxidase. Quercetin-3-O-glucose-6''-acetate has antioxidant activities.
T2858 Baicalein 491-67-8 97.25%
Baicalein
Baicalein (5,6,7-Trihydroxyflavone) is a xanthine oxidase inhibitor.
T6699 Tempol 2226-96-2 97%
Tempol
Tempol (Tanol) is a superoxide scavenger. It has anti-inflammatory, neuroprotective and analgesic effects.
T26288 Clovamide 53755-02-5 96.47%
Clovamide
Trans-Clovamide (trans-Clovamide) is a naturally occurring caffeoyl conjugate identified in the antioxidant polyphenolic fraction of cocoa (T. cacao L.) Trans-Cl...
T3621 Brigatinib 1197953-54-0 100%
Brigatinib
Brigatinib (AP-26113) is a highly potent and selective ALK inhibitor.
T0773 Febuxostat 144060-53-7 100%
Febuxostat
Febuxostat (TEI 6720) is a xanthine oxidase Inhibitor.
T1694 Oxypurinol 2465-59-0 100%
Oxypurinol
Oxypurinol is a xanthine oxidase inhibitor. Oxipurinol is potentially used for the treatment of congestive heart failure.
T77574 ROS inducer 1 2921602-31-3 100%
ROS inducer 1
ROS inducer 1 is a small molecule compound with bactericidal activity that inhibits the production of ROS in Xanthomonas axonopodis pv. citri (Xac), Xanthomonas ...
GSK2795039
T15433
GSK2795039 inhibits reactive oxygen species (ROS) production and NADPH consumption. GSK2795039 decreases apoptosis. GSK2795039 is an inhibitor of NADPH oxidase 2...
Dihydrotanshinone I
T3374
Dihydrotanshinone I (DHTS) is a natural compound extracted from Salvia miltiorrhiza Bunge used for treating of cardiovascular diseases.
JC2-11
T77579
JC2-11 is an inhibitory compound for inflammation.JC2-11 inhibits the recruitment domain-containing proteins NLRC 4, atypical in melanoma 2 (AIM 2) and atypical ...
Matairesinol
TN1916
Matairesinol has radical and superoxide scavenging activities,; it also has anti-angiogenic activity by suppressing mROS signaling , can decrease hypoxia-inducib...
Lycopene
T2864
Lycopene (ψ,ψ-Carotene) is a linear, unsaturated hydrocarbon carotenoid, the major red pigment in fruits such as tomatoes, pink grapefruit, apricots, red oranges...
Carnosic acid
T4957
Carnosic acid is a lipid absorption inhibitor, endowed with antioxidative, antimicrobial, photoprotective potential, and antiproliferative properties.
CHBO4
T77578
CHBO4 is an hMAO-B inhibitor that is potent, reversible, competitive and selective.The IC50 value of CHBO4 against hMAO-B in the CHBO assay was 0.031 μM, and the...
Alpha-Amyrin
TN1372
Alpha-Amyrin (alpha-Amyrine) is an inhibitor of trypsin and chymotrypsin with antineoplastic effects. alpha-Amyrin can be used in studies about acting as a hepat...
LYG-202
T36488
LYG-202 is a novel flavonoid with piperazine substitution and antitumor effects in vivo and in vitro.LYG-202 induced apoptosis in MCF-7, MDA-MB-231, and MDA-MB-4...
Blumeatin
TN1002
Blumeatin has antioxidant properties, free radical scavenging activity,and has xanthine oxidase (XO) inhibitory activity.
F-1
T11254
F-1 is IC50s of 2.1 nM, 2.3 nM, 1.3 nM and 3.9 nM for ALKWT, ROS1WT, ALKL1196M and ALKG1202R, respectively. F-1 is a potent ALK and ROS1 dual inhibitor, suppress...
Compound T72082(SC)
T72082
ROS-IN-1 is a mitochondrial ROS inhibitor that can be used to reduce oxidative stress or inhibit reactive oxygen species (ROS) production.
Quercetin-3-O-glucose-6''-acetate
TN2126
Quercetin-3-O-glucose-6''-acetate (6"-O-Acetylisoquercitrin) is an inhibitor of NADPH oxidase. Quercetin-3-O-glucose-6''-acetate has antioxidant activities.
Baicalein
T2858
Baicalein (5,6,7-Trihydroxyflavone) is a xanthine oxidase inhibitor.
Tempol
T6699
Tempol (Tanol) is a superoxide scavenger. It has anti-inflammatory, neuroprotective and analgesic effects.
Clovamide
T26288
Trans-Clovamide (trans-Clovamide) is a naturally occurring caffeoyl conjugate identified in the antioxidant polyphenolic fraction of cocoa (T. cacao L.) Trans-Cl...
Brigatinib
T3621
Brigatinib (AP-26113) is a highly potent and selective ALK inhibitor.
Febuxostat
T0773
Febuxostat (TEI 6720) is a xanthine oxidase Inhibitor.
Oxypurinol
T1694
Oxypurinol is a xanthine oxidase inhibitor. Oxipurinol is potentially used for the treatment of congestive heart failure.
ROS inducer 1
T77574
ROS inducer 1 is a small molecule compound with bactericidal activity that inhibits the production of ROS in Xanthomonas axonopodis pv. citri (Xac), Xanthomonas ...
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TargetMol