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target/Phosphatase/1

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  • Recombinant Protein
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    TargetMol | Recombinant_Protein
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PPP1R1A Protein, Human, Recombinant (His)
Protein Phosphatase Inhibitor 1, Protein Phosphatase 1 Regulatory Subunit 1A, PPP1R1A, IPP-1, IPP1, I-1
TMPJ-00528
Protein Phosphatase 1 Regulatory Subunit 1A (PPP1R1A) is an inhibitor of protein-phosphatase 1. PPP1R1A is a cellular regulator of eIF2 alpha phosphorylation. In hormonal control of glycogen metabolism, IPP-1 protein plays important function. Hormones can elevate intracellular cAMP level and elevate IPP-1 activity. PPP1R1A activation caused cAMP increase , cAMP control over proteins that are not directly phosphorylated by PKA following a rise in intracellular calcium. IPP-1 is inactivated by calcineurin (PP2B). Multiple domains in IPP-1 target cellular PP1 complexes.
  • $129
7-10 days
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