NOS

Nitric oxide synthases(NOSs) are a family of enzymes catalyzing the production of nitric oxide (NO) from L-arginine. NO is an important cellular signaling molecule. It helps modulate vascular tone, insulin secretion, airway tone, and peristalsis, and is involved in angiogenesis and neural development. It may function as a retrograde neurotransmitter. Nitric oxide is mediated in mammals by the calcium-calmodulin controlled isoenzymes eNOS (endothelial NOS) and nNOS (neuronal NOS).

Cat. No.	Product name	CAS No.	Purity
TN1116	Schisandrone	98619-25-1	99.84%
TN1116	Schisandrone (Arisantetralone C) is a 4-aryltetrahydrofuran lignan extracted from the dried fruit of Schisandra chinensis.
T5676	(Z)-SU4312	90828-16-3	99.84%
T5676	(Z)-SU4312 is a inhibitor of MAO-B and NOS(IC50 value of 0.2 μM, 19.0μM,respectively).
TN3609	Catalposide	6736-85-2	99.82%
TN3609	Catalposide is a potent inducer of (HO)-1 isolated from Catalpa ovate G. Don (Bignoniaceae). Catalposide possesses antioxidant, anti-apoptotic, anti-microbial, a...
TN2232	Soyasaponin Ab	118194-13-1	99.79%
TN2232	Soyasaponin Ab may represent a viable candidate for effective vaccine adjuvant, TLR4 receptor dependent pathway may be involved in immune stimulatory effects of ...
T0344	Miconazole	22916-47-8	99.78%
T0344	Miconazole (R18134) is an imidazole antifungal agent that is used topically and by intravenous infusion.
T4953	Neotuberostemonine	143120-46-1	99.73%
T4953	Neotuberostemonine (NTS) is one of the main antitussive alkaloids in the root of Stemona tuberosa Lour, it has a significant protective effect on bleomycin (BLM)...
T37696	NOS1-IN-1	357965-99-2	99.7%
T37696	NOS1-IN-1（nNOS Inhibitor I） is a potent, selective and cell permeable nNOS inhibitor (Ki: 120 nM).NOS1-IN-1 has a Ki value of 39 μM for eNOS and 325 μM for iNOS....
T83625	INOS-IN-14	945762-00-5	99.68%
T83625	iNOS-IN-14 (3-bromo-1H-indazole-7-carbonitrile) is a potent nitric oxide synthase (NOS) inhibitor that inhibits the NADPH oxidase activity of nNOS.
T8213	Isolinderalactone	957-66-4	99.62%
T8213	Isolinderalactone shows anti-inflammatory and anticancer capacity, and it exhibits moderate iNOS inhibitory activity, with the IC50 value of 0.30 uM.
T3408	Syringin	118-34-3	99.56%
T3408	Syringin (eleutheroside-b) is a compound with antitumor, antiproliferative, immunomodulatory and platelet aggregation inhibiting effects.
T19916	TRIM	25371-96-4	99.51%
T19916	TRIM (1-(2-Trifluoromethylphenyl)imidazole) is an inhibitor of nNOS.
TN1238	3,4-O-Isopropylidene-shikimic acid	183075-03-8	99.47%
TN1238	3,4-O-Isopropylidene-shikimic acid (3,4-O-Isopropylidene shikimic acid) has significant anti-inflammatory, anti-thrombosis, antioxidant, analgesic effects, it ha...
TN2139	Regaloside B	114420-67-6	99.4%
TN2139	Regaloside B, a phenylpropanoid isolated from Lilium longiflorum, exhibits anti-inflammatory activity by inhibiting the expression of iNOS (inducible nitric oxid...
TN1962	Myricetin 3-O-galactoside	15648-86-9	99.38%
TN1962	Myricetin 3-O-galactoside (Myricetin 3-O-beta-D-galactopyranoside) can inhibit xanthine oxidase (xanthine oxidase; XO) activity, lipid peroxidation and scavengin...
T6570	L-NAME hydrochloride	51298-62-5	99.37%
T6570	L-NAME hydrochloride (L-NAME HCl), a cell-permeable NO synthase inhibitor, displays Ki values of 4.4 μM, 15 nM, and 39 nM, for iNOS (mouse) , nNOS (bovine) , and...
T5807	Stylopine hydrochloride	96087-21-7	99.34%
T5807	Stylopine is a protoberberine-type alkaloid that has potential biological activities, including anti-inflammatory activity.
TN4234	Hydrangenol	480-47-7	99.33%
TN4234	Hydrangenol is a natural product and can be isolated from Hydrangea serrata leaves. Hydrangenol is an antiphotoaging compound with oral activity. Hydrangenol can...
TN1465	Cannabigerol	25654-31-3	99.23%
TN1465	Cannabigerol is a high affinity α±2-adrenergic receptor agonist, moderate affinity 5-HT1A receptor antagonist, and low affinity CB1 receptor antagonist ; also bi...
T69356	Cindunistat	364067-22-1	99.22%
T69356	Cindunistat (free base) is an orally available selective iNOS inhibitor for the study of arthritis.
TN1516	Cnidicin	14348-21-1	99.16%
TN1516	Cnidicin has anti-allergic and anti-inflammatory activity, it inhibits the degranulation of mast cell and the NO generation in RAW 264.7 cells(IC50 value, 7.5 mi...