AChE

Acetylcholinesterase, also known as AChE, AChase or acetylhydrolase, is the primary cholinesterase in the body. It is an enzyme that catalyzes the breakdown of acetylcholine and some other choline esters that function as neurotransmitters. AChE is found at mainly neuromuscular junctions and in chemical synapses of the cholinergic type, where its activity serves to terminate synaptic transmission. It belongs to the carboxylesterase family of enzymes. It is the primary target of inhibition by organophosphorus compounds such as nerve agents and pesticides.

Cat. No.	Product name	CAS No.	Purity
T3S1612	Kuwanon G	75629-19-5	98.47%
T3S1612	1. Kuwanon G as dual inhibitors of PTP1B and α-glucosidase enzymes, as well as insulin sensitizers, it may potentially be utilized as an effective treatment for ...
T5S2254	Swertianolin	23445-00-3	98.5%
T5S2254	1. Swertianolin, mangiferin, rhodenthoside A-C, isoorientin, isovitexin, and amarogentin would serve as potential chemotaxonomic markers to differentiate Gentian...
T20847	Thiobencarb	28249-77-6	98.68%
T20847	Thiobencarb, a thiocarbamate cholinesterase inhibitor, is used as a pre-emergence herbicide.
T3872	Nodakenin	495-31-8	98.93%
T3872	Nodakenin is a compound with anti-allergic and anti-inflammatory activities.
T5S1408	Pteryxin	13161-75-6	98.94%
T5S1408	(+)-Pteryxin has muscle-relaxant props. (+)-Pteryxin shows hepatoprotective and nitric oxide prodn. inhibitory activity.
T3933	Jatrorrhizine	3621-38-3	99.06%
T3933	Jatrorrhizine is a protoberberine alkaloid isolated from Enantia chlorantha (Annonaceae) and other species. It was found to have antimicrobial and antifungal act...
T13681	Epi-galantamine	1668-85-5	99.07%
T13681	Epi-galantamine is an alkaloid isolated from the bulbs and flowers of Caucasian snowdrop (Galanthus woronowii). Epi-galantamine inhibits AChE with an EC50 of 45....
TN6783	Corysamine chloride	11028-77-6	99.1%
TN6783	Corysamine chloride was identified to inhibit the activity of ACHE.
T4852	Trimyristin	555-45-3	99.11%
T4852	Within the cell, glyceryl trimyristate is primarily located in the membrane (predicted from logP) and adiposome. glyceryl trimyristate exists in all eukaryotes, ...
T0086	Galanthamine hydrobromide	1953-04-4	99.19%
T0086	Galanthamine hydrobromide, a long-acting and centrally active AChE inhibitor (IC50:410 nM), is an allosteric potentiator at neuronal nicotinic ACh receptors.
T11351	Galanthamine N-Oxide	134332-50-6	99.29%
T11351	Galanthamine N-Oxide inhibits electric eel acetylcholinesterase (AChE) with an EC50 of 26.2 μM. Galanthamine N-Oxide is a prominent inhibitor of substrate accomm...
T1612	Neostigmine methyl sulfate	51-60-5	99.34%
T1612	Hodostin is a reversible inhibitor of acetylcholinesterase, can not cross the blood-brain barrier, used in the treatment of myasthenia gravis.
TN1589	Dihydrowithaferin A	5589-41-3	99.39%
TN1589	Dihydrowithaferin A is a withanolide isolated from Withania somnifera with activity against acetylcholinesterase (AChE). Dihydrowithaferin A in the diet may prev...
T4S1024	Picfeltarraenin IB	97230-46-1	99.39%
T4S1024	1. Picfeltarraenin IB and Picfeltarraenin IA displayes no cytotoxic activity in vitro human tumor cell line panel.
T2319	Acotiamide monohydrochloride trihydrate	773092-05-0	99.48%
T2319	Acotiamide Hydrochloride is the hydrochloride salt form of acotiamide, a prokinetic agent with gastrointestinal (GI) motility-enhancing activity. Although the ex...
T0269	Dichlorisone Acetate	79-61-8	99.51%
T0269	Dichlorisone Acetate is a synthetic glucocorticoid corticosteroid with anti-inflammatory activity.
T0713	Drofenine hydrochloride	548-66-3	99.53%
T0713	Drofenine hydrochloride is an effective competitive inhibitor of BChE (Ki value: 3 uM).
T3852	Rhodiosin	86831-54-1	99.55%
T3852	Rhodiosin is a compound with antioxidant activity.
TN1030	N-p-trans-Coumaroyltyramine	36417-86-4	99.56%
TN1030	N-p-trans-Coumaroyltyramine is a natural product, is an acetylcholinesterase (AChE) inhibitor with an an IC50 of 122 μM. N-p-trans-Coumaroyltyramine exhibits ant...
T5S2361	Epiberberine	6873-09-2	99.58%
T5S2361	1. Epiberberine may be caused drug interactions based on CYP2D6 enzyme. 2. Epiberberine has anti-adipogenic effect is mediated by downregulation of the Raf/MEK1/...