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AChE

Acetylcholinesterase, also known as AChE, AChase or acetylhydrolase, is the primary cholinesterase in the body. It is an enzyme that catalyzes the breakdown of acetylcholine and some other choline esters that function as neurotransmitters. AChE is found at mainly neuromuscular junctions and in chemical synapses of the cholinergic type, where its activity serves to terminate synaptic transmission. It belongs to the carboxylesterase family of enzymes. It is the primary target of inhibition by organophosphorus compounds such as nerve agents and pesticides.
Cat. No. Product name CAS No. Purity Chemical Structure
TN1589 Dihydrowithaferin A 5589-41-3 98%
Dihydrowithaferin A is a withanolide isolated from Withania somnifera with activity against acetylcholinesterase (AChE). Dihydrowithaferin A in the diet may prev...
T11351 Galanthamine N-Oxide 134332-50-6 98%
Galanthamine N-Oxide inhibits electric eel acetylcholinesterase (AChE) with an EC50 of 26.2 μM. Galanthamine N-Oxide is a prominent inhibitor of substrate accomm...
T2846 Isoimperatorin 482-45-1 98%
Isoimperatorin is an anti-inflammatory agent, exhibits significant inhibitory effects on acetylcholinesterase (AChE).
T4852 Trimyristin 555-45-3 98%
Within the cell, glyceryl trimyristate is primarily located in the membrane (predicted from logP) and adiposome. glyceryl trimyristate exists in all eukaryotes, ...
TN6783 Corysamine chloride 11028-77-6 98%
Corysamine chloride was identified to inhibit the activity of ACHE.
T13681 Epi-galantamine 1668-85-5 98%
Epi-galantamine is an alkaloid isolated from the bulbs and flowers of Caucasian snowdrop (Galanthus woronowii). Epi-galantamine inhibits AChE with an EC50 of 45....
T0269 Dichlorisone Acetate 79-61-8 98%
Dichlorisone Acetate is a synthetic glucocorticoid corticosteroid with anti-inflammatory activity.
T20847 Thiobencarb 28249-77-6 98%
Thiobencarb, a thiocarbamate cholinesterase inhibitor, is used as a pre-emergence herbicide.
T3933 Jatrorrhizine 3621-38-3 98%
Jatrorrhizine is a protoberberine alkaloid isolated from Enantia chlorantha (Annonaceae) and other species. It was found to have antimicrobial and antifungal act...
T11366 Garcinol 78824-30-3 98%
Garcinol also inhibits histone acetyltransferases (HATs, IC50= 7 μM) and p300/CPB-associated factor (PCAF, IC50 = 5 μM). Garcinol has anti-inflammatory and anti-...
T4439 Sn-Glycero-3-phosphocholine 28319-77-9 98%
sn-Glycero-3-phosphocholine is a natural choline compound found in the brain and in milk. It is also a parasympathomimetic acetylcholine precursor which may have...
T5S2361 Epiberberine 6873-09-2 98%
1. Epiberberine may be caused drug interactions based on CYP2D6 enzyme. 2. Epiberberine has anti-adipogenic effect is mediated by downregulation of the Raf/MEK1/...
TN1011 Rhodionin 85571-15-9 98%
Rhodionin and rhodionin can inhibit cytochrome P450 2D6 non-competitively with high specificity which could have implications for interactions with co-administer...
T22329 Ethyl (triphenylphosphoranylidene) acetate 1099-45-2 98%
Ethyl (triphenylphosphoranylidene) acetate may act as an cholinesterase inhibitor that inhibits AChE and BChE.
TN2443 Chikusetsusaponin Ib 59252-87-8 98%
Chikusetsusaponin Ib is an inhibitor of AChE and can be used in studies about anti-Alzheimer's diseases.
T9862 Pseudocoptisine chloride 30044-78-1 98%
Pseudocoptisine chloride is isolated from Corydalis Tuber with anti-inflammatory and anti-amnestic properties. Pseudocoptisine chloride inhibits acetylcholineste...
T6S2356 Corynoline 18797-79-0 98%
1. Corynoline is an acetylcholinesterase inhibitor.
T13469 (±)-Huperzine A 120786-18-7 98%
(±)-Huperzine A is an active Lycopodium alkaloid extracted from traditional Chinese herbs. (±)-Huperzine A is a selective and reversible inhibitor of AChE and ca...
T3767 Polygalacic acid 22338-71-2 98%
Polygalacic acid(PA) significantly improves cholinergic system reactivity, as indicated by decreased acetylcholinesterase (AChE) activity, increases choline acet...
T1635 Fenchlorphos 299-84-3 98%
Fenchlorphos is a cholinesterase inhibitor, used as an insecticide.
Dihydrowithaferin A
TN1589
Dihydrowithaferin A is a withanolide isolated from Withania somnifera with activity against acetylcholinesterase (AChE). Dihydrowithaferin A in the diet may prev...
Galanthamine N-Oxide
T11351
Galanthamine N-Oxide inhibits electric eel acetylcholinesterase (AChE) with an EC50 of 26.2 μM. Galanthamine N-Oxide is a prominent inhibitor of substrate accomm...
Isoimperatorin
T2846
Isoimperatorin is an anti-inflammatory agent, exhibits significant inhibitory effects on acetylcholinesterase (AChE).
Trimyristin
T4852
Within the cell, glyceryl trimyristate is primarily located in the membrane (predicted from logP) and adiposome. glyceryl trimyristate exists in all eukaryotes, ...
Corysamine chloride
TN6783
Corysamine chloride was identified to inhibit the activity of ACHE.
Epi-galantamine
T13681
Epi-galantamine is an alkaloid isolated from the bulbs and flowers of Caucasian snowdrop (Galanthus woronowii). Epi-galantamine inhibits AChE with an EC50 of 45....
Dichlorisone Acetate
T0269
Dichlorisone Acetate is a synthetic glucocorticoid corticosteroid with anti-inflammatory activity.
Thiobencarb
T20847
Thiobencarb, a thiocarbamate cholinesterase inhibitor, is used as a pre-emergence herbicide.
Jatrorrhizine
T3933
Jatrorrhizine is a protoberberine alkaloid isolated from Enantia chlorantha (Annonaceae) and other species. It was found to have antimicrobial and antifungal act...
Garcinol
T11366
Garcinol also inhibits histone acetyltransferases (HATs, IC50= 7 μM) and p300/CPB-associated factor (PCAF, IC50 = 5 μM). Garcinol has anti-inflammatory and anti-...
sn-Glycero-3-phosphocholine
T4439
sn-Glycero-3-phosphocholine is a natural choline compound found in the brain and in milk. It is also a parasympathomimetic acetylcholine precursor which may have...
Epiberberine
T5S2361
1. Epiberberine may be caused drug interactions based on CYP2D6 enzyme. 2. Epiberberine has anti-adipogenic effect is mediated by downregulation of the Raf/MEK1/...
Rhodionin
TN1011
Rhodionin and rhodionin can inhibit cytochrome P450 2D6 non-competitively with high specificity which could have implications for interactions with co-administer...
Ethyl (triphenylphosphoranylidene) acetate
T22329
Ethyl (triphenylphosphoranylidene) acetate may act as an cholinesterase inhibitor that inhibits AChE and BChE.
Chikusetsusaponin Ib
TN2443
Chikusetsusaponin Ib is an inhibitor of AChE and can be used in studies about anti-Alzheimer's diseases.
Pseudocoptisine chloride
T9862
Pseudocoptisine chloride is isolated from Corydalis Tuber with anti-inflammatory and anti-amnestic properties. Pseudocoptisine chloride inhibits acetylcholineste...
Corynoline
T6S2356
1. Corynoline is an acetylcholinesterase inhibitor.
(±)-Huperzine A
T13469
(±)-Huperzine A is an active Lycopodium alkaloid extracted from traditional Chinese herbs. (±)-Huperzine A is a selective and reversible inhibitor of AChE and ca...
Polygalacic acid
T3767
Polygalacic acid(PA) significantly improves cholinergic system reactivity, as indicated by decreased acetylcholinesterase (AChE) activity, increases choline acet...
Fenchlorphos
T1635
Fenchlorphos is a cholinesterase inhibitor, used as an insecticide.
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