AChE

Acetylcholinesterase, also known as AChE, AChase or acetylhydrolase, is the primary cholinesterase in the body. It is an enzyme that catalyzes the breakdown of acetylcholine and some other choline esters that function as neurotransmitters. AChE is found at mainly neuromuscular junctions and in chemical synapses of the cholinergic type, where its activity serves to terminate synaptic transmission. It belongs to the carboxylesterase family of enzymes. It is the primary target of inhibition by organophosphorus compounds such as nerve agents and pesticides.

Cat. No.	Product name	CAS No.	Purity
TN1589	Dihydrowithaferin A	5589-41-3	98%
TN1589	Dihydrowithaferin A is a withanolide isolated from Withania somnifera with activity against acetylcholinesterase (AChE). Dihydrowithaferin A in the diet may prev...
T11351	Galanthamine N-Oxide	134332-50-6	98%
T11351	Galanthamine N-Oxide inhibits electric eel acetylcholinesterase (AChE) with an EC50 of 26.2 μM. Galanthamine N-Oxide is a prominent inhibitor of substrate accomm...
T2846	Isoimperatorin	482-45-1	98%
T2846	Isoimperatorin is an anti-inflammatory agent, exhibits significant inhibitory effects on acetylcholinesterase (AChE).
T4852	Trimyristin	555-45-3	98%
T4852	Within the cell, glyceryl trimyristate is primarily located in the membrane (predicted from logP) and adiposome. glyceryl trimyristate exists in all eukaryotes, ...
TN6783	Corysamine chloride	11028-77-6	98%
TN6783	Corysamine chloride was identified to inhibit the activity of ACHE.
T13681	Epi-galantamine	1668-85-5	98%
T13681	Epi-galantamine is an alkaloid isolated from the bulbs and flowers of Caucasian snowdrop (Galanthus woronowii). Epi-galantamine inhibits AChE with an EC50 of 45....
T0269	Dichlorisone Acetate	79-61-8	98%
T0269	Dichlorisone Acetate is a synthetic glucocorticoid corticosteroid with anti-inflammatory activity.
T20847	Thiobencarb	28249-77-6	98%
T20847	Thiobencarb, a thiocarbamate cholinesterase inhibitor, is used as a pre-emergence herbicide.
T3933	Jatrorrhizine	3621-38-3	98%
T3933	Jatrorrhizine is a protoberberine alkaloid isolated from Enantia chlorantha (Annonaceae) and other species. It was found to have antimicrobial and antifungal act...
T11366	Garcinol	78824-30-3	98%
T11366	Garcinol also inhibits histone acetyltransferases (HATs, IC50= 7 μM) and p300/CPB-associated factor (PCAF, IC50 = 5 μM). Garcinol has anti-inflammatory and anti-...
T4439	Sn-Glycero-3-phosphocholine	28319-77-9	98%
T4439	sn-Glycero-3-phosphocholine is a natural choline compound found in the brain and in milk. It is also a parasympathomimetic acetylcholine precursor which may have...
T5S2361	Epiberberine	6873-09-2	98%
T5S2361	1. Epiberberine may be caused drug interactions based on CYP2D6 enzyme. 2. Epiberberine has anti-adipogenic effect is mediated by downregulation of the Raf/MEK1/...
TN1011	Rhodionin	85571-15-9	98%
TN1011	Rhodionin and rhodionin can inhibit cytochrome P450 2D6 non-competitively with high specificity which could have implications for interactions with co-administer...
T22329	Ethyl (triphenylphosphoranylidene) acetate	1099-45-2	98%
T22329	Ethyl (triphenylphosphoranylidene) acetate may act as an cholinesterase inhibitor that inhibits AChE and BChE.
TN2443	Chikusetsusaponin Ib	59252-87-8	98%
TN2443	Chikusetsusaponin Ib is an inhibitor of AChE and can be used in studies about anti-Alzheimer's diseases.
T9862	Pseudocoptisine chloride	30044-78-1	98%
T9862	Pseudocoptisine chloride is isolated from Corydalis Tuber with anti-inflammatory and anti-amnestic properties. Pseudocoptisine chloride inhibits acetylcholineste...
T6S2356	Corynoline	18797-79-0	98%
T6S2356	1. Corynoline is an acetylcholinesterase inhibitor.
T13469	(±)-Huperzine A	120786-18-7	98%
T13469	(±)-Huperzine A is an active Lycopodium alkaloid extracted from traditional Chinese herbs. (±)-Huperzine A is a selective and reversible inhibitor of AChE and ca...
T3767	Polygalacic acid	22338-71-2	98%
T3767	Polygalacic acid(PA) significantly improves cholinergic system reactivity, as indicated by decreased acetylcholinesterase (AChE) activity, increases choline acet...
T1635	Fenchlorphos	299-84-3	98%
T1635	Fenchlorphos is a cholinesterase inhibitor, used as an insecticide.