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AChE

Acetylcholinesterase, also known as AChE, AChase or acetylhydrolase, is the primary cholinesterase in the body. It is an enzyme that catalyzes the breakdown of acetylcholine and some other choline esters that function as neurotransmitters. AChE is found at mainly neuromuscular junctions and in chemical synapses of the cholinergic type, where its activity serves to terminate synaptic transmission. It belongs to the carboxylesterase family of enzymes. It is the primary target of inhibition by organophosphorus compounds such as nerve agents and pesticides.
Cat. No. Product name CAS No. Purity Chemical Structure
T3S1612 Kuwanon G 75629-19-5 98.47%
1. Kuwanon G as dual inhibitors of PTP1B and α-glucosidase enzymes, as well as insulin sensitizers, it may potentially be utilized as an effective treatment for ...
T5S2254 Swertianolin 23445-00-3 98.5%
1. Swertianolin, mangiferin, rhodenthoside A-C, isoorientin, isovitexin, and amarogentin would serve as potential chemotaxonomic markers to differentiate Gentian...
T20847 Thiobencarb 28249-77-6 98.68%
Thiobencarb, a thiocarbamate cholinesterase inhibitor, is used as a pre-emergence herbicide.
T3872 Nodakenin 495-31-8 98.93%
Nodakenin is a compound with anti-allergic and anti-inflammatory activities.
T5S1408 Pteryxin 13161-75-6 98.94%
(+)-Pteryxin has muscle-relaxant props. (+)-Pteryxin shows hepatoprotective and nitric oxide prodn. inhibitory activity.
T3933 Jatrorrhizine 3621-38-3 99.06%
Jatrorrhizine is a protoberberine alkaloid isolated from Enantia chlorantha (Annonaceae) and other species. It was found to have antimicrobial and antifungal act...
T13681 Epi-galantamine 1668-85-5 99.07%
Epi-galantamine is an alkaloid isolated from the bulbs and flowers of Caucasian snowdrop (Galanthus woronowii). Epi-galantamine inhibits AChE with an EC50 of 45....
TN6783 Corysamine chloride 11028-77-6 99.1%
Corysamine chloride was identified to inhibit the activity of ACHE.
T4852 Trimyristin 555-45-3 99.11%
Within the cell, glyceryl trimyristate is primarily located in the membrane (predicted from logP) and adiposome. glyceryl trimyristate exists in all eukaryotes, ...
T0086 Galanthamine hydrobromide 1953-04-4 99.19%
Galanthamine hydrobromide, a long-acting and centrally active AChE inhibitor (IC50:410 nM), is an allosteric potentiator at neuronal nicotinic ACh receptors.
T11351 Galanthamine N-Oxide 134332-50-6 99.29%
Galanthamine N-Oxide inhibits electric eel acetylcholinesterase (AChE) with an EC50 of 26.2 μM. Galanthamine N-Oxide is a prominent inhibitor of substrate accomm...
T1612 Neostigmine methyl sulfate 51-60-5 99.34%
Hodostin is a reversible inhibitor of acetylcholinesterase, can not cross the blood-brain barrier, used in the treatment of myasthenia gravis.
TN1589 Dihydrowithaferin A 5589-41-3 99.39%
Dihydrowithaferin A is a withanolide isolated from Withania somnifera with activity against acetylcholinesterase (AChE). Dihydrowithaferin A in the diet may prev...
T4S1024 Picfeltarraenin IB 97230-46-1 99.39%
1. Picfeltarraenin IB and Picfeltarraenin IA displayes no cytotoxic activity in vitro human tumor cell line panel.
T2319 Acotiamide monohydrochloride trihydrate 773092-05-0 99.48%
Acotiamide Hydrochloride is the hydrochloride salt form of acotiamide, a prokinetic agent with gastrointestinal (GI) motility-enhancing activity. Although the ex...
T0269 Dichlorisone Acetate 79-61-8 99.51%
Dichlorisone Acetate is a synthetic glucocorticoid corticosteroid with anti-inflammatory activity.
T0713 Drofenine hydrochloride 548-66-3 99.53%
Drofenine hydrochloride is an effective competitive inhibitor of BChE (Ki value: 3 uM).
T3852 Rhodiosin 86831-54-1 99.55%
Rhodiosin is a compound with antioxidant activity.
TN1030 N-p-trans-Coumaroyltyramine 36417-86-4 99.56%
N-p-trans-Coumaroyltyramine is a natural product, is an acetylcholinesterase (AChE) inhibitor with an an IC50 of 122 μM. N-p-trans-Coumaroyltyramine exhibits ant...
T5S2361 Epiberberine 6873-09-2 99.58%
1. Epiberberine may be caused drug interactions based on CYP2D6 enzyme. 2. Epiberberine has anti-adipogenic effect is mediated by downregulation of the Raf/MEK1/...
kuwanon G
T3S1612
1. Kuwanon G as dual inhibitors of PTP1B and α-glucosidase enzymes, as well as insulin sensitizers, it may potentially be utilized as an effective treatment for ...
Swertianolin
T5S2254
1. Swertianolin, mangiferin, rhodenthoside A-C, isoorientin, isovitexin, and amarogentin would serve as potential chemotaxonomic markers to differentiate Gentian...
Thiobencarb
T20847
Thiobencarb, a thiocarbamate cholinesterase inhibitor, is used as a pre-emergence herbicide.
Nodakenin
T3872
Nodakenin is a compound with anti-allergic and anti-inflammatory activities.
Pteryxin
T5S1408
(+)-Pteryxin has muscle-relaxant props. (+)-Pteryxin shows hepatoprotective and nitric oxide prodn. inhibitory activity.
Jatrorrhizine
T3933
Jatrorrhizine is a protoberberine alkaloid isolated from Enantia chlorantha (Annonaceae) and other species. It was found to have antimicrobial and antifungal act...
Epi-galantamine
T13681
Epi-galantamine is an alkaloid isolated from the bulbs and flowers of Caucasian snowdrop (Galanthus woronowii). Epi-galantamine inhibits AChE with an EC50 of 45....
Corysamine chloride
TN6783
Corysamine chloride was identified to inhibit the activity of ACHE.
Trimyristin
T4852
Within the cell, glyceryl trimyristate is primarily located in the membrane (predicted from logP) and adiposome. glyceryl trimyristate exists in all eukaryotes, ...
Galanthamine hydrobromide
T0086
Galanthamine hydrobromide, a long-acting and centrally active AChE inhibitor (IC50:410 nM), is an allosteric potentiator at neuronal nicotinic ACh receptors.
Galanthamine N-Oxide
T11351
Galanthamine N-Oxide inhibits electric eel acetylcholinesterase (AChE) with an EC50 of 26.2 μM. Galanthamine N-Oxide is a prominent inhibitor of substrate accomm...
Neostigmine methyl sulfate
T1612
Hodostin is a reversible inhibitor of acetylcholinesterase, can not cross the blood-brain barrier, used in the treatment of myasthenia gravis.
Dihydrowithaferin A
TN1589
Dihydrowithaferin A is a withanolide isolated from Withania somnifera with activity against acetylcholinesterase (AChE). Dihydrowithaferin A in the diet may prev...
Picfeltarraenin IB
T4S1024
1. Picfeltarraenin IB and Picfeltarraenin IA displayes no cytotoxic activity in vitro human tumor cell line panel.
Acotiamide monohydrochloride trihydrate
T2319
Acotiamide Hydrochloride is the hydrochloride salt form of acotiamide, a prokinetic agent with gastrointestinal (GI) motility-enhancing activity. Although the ex...
Dichlorisone Acetate
T0269
Dichlorisone Acetate is a synthetic glucocorticoid corticosteroid with anti-inflammatory activity.
Drofenine hydrochloride
T0713
Drofenine hydrochloride is an effective competitive inhibitor of BChE (Ki value: 3 uM).
Rhodiosin
T3852
Rhodiosin is a compound with antioxidant activity.
N-p-trans-Coumaroyltyramine
TN1030
N-p-trans-Coumaroyltyramine is a natural product, is an acetylcholinesterase (AChE) inhibitor with an an IC50 of 122 μM. N-p-trans-Coumaroyltyramine exhibits ant...
Epiberberine
T5S2361
1. Epiberberine may be caused drug interactions based on CYP2D6 enzyme. 2. Epiberberine has anti-adipogenic effect is mediated by downregulation of the Raf/MEK1/...
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