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xr9051

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  • Inhibitors & Agonists
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XR9051
T68737762219-35-2
XR9051 is as a potent modulator of P-glycoprotein (P-gp)-mediated multidrug resistance (MDR) following a synthetic chemistry programme based on a natural product lead compound. XR9051 was shown to be a potent inhibitor of the binding of the cytotoxic to P-glycoprotein (EC50 = 1.4 + - 0.5 nM). XR9051 reverses the MDR phenotype through direct interaction with P-glycoprotein.
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8-10 weeks
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XR9051 Hydrochloride
T29169180422-22-4
XR9051 Hydrochloride, a potent modulator of P-glycoprotein-mediated multidrug resistance (MDR), inhibits the binding of cytotoxics to P-glycoprotein.
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8-10 weeks
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