vsv

VSV-G Peptide acetate(103425-05-4 free base) is a 11 amino acid peptide derived from the Vesicular Stomatitis viral glycoprotein.

VSV-G is a vesicular stomatitis virus G (VSV-G) protein fragment. VSV-G protein is commonly used in biomedical research to pseudotype retroviral and lentiviral vectors, conveying the ability to transduce a broad range of mammalian cell types with genes of

Diphyllin could be characterized as a new V-ATPase inhibitor in treating gastric cancer and inhibiting the phosphorylation of LRP6 in Wnt/β-catenin signaling.

VSV-G Peptide is a 11 amino acid peptide derived from the Vesicular Stomatitis viral glycoprotein .

H2-D b restricted epitopesVSVNucleoprotein (52-59) is a nonapeptide derived from the nucleoprotein of Vesicular Stomatitis Virus (VSV). It binds to MHC class I molecules to present itself to CD8+ T cells, thereby activating cytotoxic T lymphocytes (CTLs) that recognize and destroy cells expressing the corresponding antigen. This epitope is instrumental in the development of CTL vaccines against the Ebola virus.

KYGVSVQDI Acetate is the DNA sequence encoding the MHC class I-restricted peptide p60(217-225) from Listeria monocytogenes.

UNC0638 hydrate selectively inhibits G9a and GLP histone methyltransferases with IC50 values of 15 nM and 19 nM, respectively. It is effective in inhibiting invasion and migration of TNBC cells in vitro. Additionally, UNC0638 hydrate acts as an inhibitor of EHMT1/2 and induces the expression of fetal hemoglobin (HbF) in cultures of human erythroid progenitor cells. Furthermore, it exhibits antiviral activity against FMDV (foot-and-mouth disease virus) and VSV (vesicular stomatitis virus), demonstrating remarkable potency and selectivity across various epigenetic and non-epigenetic targets.

SMU-V18 is a vesicular stomatitis virus (VSV) inhibitor with an EC50 of 6.2 μM. It suppresses VSV-GFP fluorescence intensity, viral mRNA/protein expression, and progeny virus replication. SMU-V18 interferes with the early stages of viral infection and is effective against wild-type VSV (VSV-WT). Additionally, it suppresses VSV-GFP in mouse tissues and extends survival in mice. SMU-V18 is useful for studying vesicular stomatitis virus (VSV) infections.

Pitstop 2d is a Clathrin inhibitor with an IC50 of less than 2 μM. It binds to the Clathrin N-terminal β-propeller domain, thereby inhibiting Clathrin's function and dynamics and blocking the entry of VSV. Pitstop 2d specifically inhibits clathrin-mediated endocytosis (Endocytosis) and does not interfere with non-clathrin-dependent endocytic processes.

Pitstop 2c is a Clathrin inhibitor with an IC50 of less than 2 μM. It binds to the Clathrin N-terminal β-propeller domain, impairing Clathrin's function and dynamics, and blocking the entry of vesicular stomatitis virus (VSV). Pitstop 2c inhibits clathrin-mediated endocytosis (Endocytosis) but does not inhibit non-clathrin-dependent endocytosis.

CL385319 is a potent inhibitor of H5N1 avian influenza A virus infection by blocking viral entry. CL-385319 is effective in inhibiting infection of highly pathogenic H5N1 influenza A virus in Madin-Darby Canine Kidney (MDCK) cells with an IC50 of 27.03±2.

SARS-CoV-2-IN-55 (compound 65) is a SARS-CoV-2 inhibitor with low cytotoxicity, characterized by an IC50 of 0.3 μM, and acts through direct interaction with VSV-S pseudoparticles [1].

Mesoporphyrin IX (dihydrochloride), a photosensitizer, is effective in modifying liposomes and inserting into lipid vesicles. It disrupts the viral membrane structure of vesicular stomatitis virus (VSV), inducing cross-linking of VSV glycoproteins and thereby inhibiting viral activity.

9-Methylstreptimidone (AntibioticTS 885; NSC 248958) is a microbial metabolite initially isolated from Streptomyces S-885, known for its antifungal and antiviral properties. It is effective against various fungi, such as S. sake, S. fragilis, R. rubra, T. rubra, and C. albidus, with a MIC of 4-20 μg/mL. Additionally, it shows in vitro antiviral activity against poliovirus, vesicular stomatitis virus (VSV), and Newcastle disease virus (NDV) with a MIC of 0.02 μg/mL. Administering 9-Methylstreptimidone before infection can increase survival rates in mouse models infected with influenza A2 (H2N2) or Candida albicans.