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ucm-1336

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  • Inhibitors & Agonists
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UCM-1336
3,3′-(Octylimino)bis[N-phenylpropanamide]
T99351621535-90-7In house
UCM-1336 (3,3′-(Octylimino)bis[N-phenylpropanamide]) is a potent ICMT inhibitor with an IC50 of 2 μM which is selective against the other enzymes involved in the post-translational modifications of Ras.
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UCM-13369
T875912921944-77-4
UCM-13369 (Compound 4b) serves as an NPM1 inhibitor, effectively downregulating the pathway linked to mutant NPM1 C+ by specifically targeting the C-terminal DNA-binding domain of NPM1 C+. It induces apoptosis in AML cell lines and primary cells, making it a valuable tool for AML research [1].
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10-14 weeks
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