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By Target- CDK
- PI3K(1)
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Results for "
thz 1
" in TargetMol Product Catalog- Inhibitors & Agonists6
(E/Z)-THZ1 2HCl
(E Z)-THZ1 Dihydrochloride, (E Z)-THZ1 2HCl
T353322095433-94-4
THZ1 2HCl (THZ1 Dihydrochloride) is a selective, covalent, and allosteric inhibitor of CDK7 with an IC50 of 3.2 nM. THZ1 2HCl has antiproliferative effects on a variety of cancer cell lines.
- $40
Size
QTY
THZ1
THZ1 2HCl, CDK7 inhibitor
T36641604810-83-4
THZ1 (CDK7 inhibitor) is a selective covalent inhibitor of CDK7, exhibiting binding affinity to the cysteine residue located at the outer end of the classical kinase domain, thus conferring high selectivity for CDK7, with an IC50 of 3.2 nM.
- $81
Size
QTY
THZ2
CDK7-IN-1
T72961604810-84-5
THZ2 (CDK7-IN-1), an analog of THZ1, is a potent and selective CDK7 inhibitor(IC50:13.9 nM),with the potential to treat Triple-negative breast cancer (TNBC).
- $77
Size
QTY
THZ1-R
THZ1R
T131531621523-07-6
THZ1-R is a non-covalent active analogue of THZ1, with the acrylamide group removed from THZ1, losing its ability to covalently bind to the C312 cysteine residue of CDK7. Its CDK7 inhibitory activity is weaker than that of THZ1.
- $499
Size
QTY
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