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By Target- Prostaglandin Receptor
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Results for "
thielavin a
" in TargetMol Product Catalog- Inhibitors & Agonists2
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Thielavin A
T3777471950-66-8
Thielavin A is a fungal metabolite originally isolated from T. terricola that is related to thielavin B . Thielavin A inhibits COX, blocking both the conversion of arachidonic acid to prostaglandin H2 and the conversion of PGH2 to PGE2 . Thielavin A also inhibits glucose-6-phosphatase in rat liver microsomes (IC50 = 4.6 μM). It is a non-competitive inhibitor of α-glucosidase from S. cerevisiae (IC50 = 23.8 μM; Ki = 27.8 μM).
- $880
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Thielavin B
T7306671950-67-9
Thielavin B, produced by Thielavia terricola, functions as an inhibitor of prostaglandin biosynthesis, specifically targeting the synthesis of prostaglandin E2 from the endoperoxide. It demonstrates significant efficacy in reducing carrageenan-induced edema in rats when administered intravenously.
- $2,720
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