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By Target- COX
- Lipoxygenase(1)
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Results for "
tepoxalin
" in TargetMol Product Catalog- Inhibitors & Agonists1
Tepoxalin
RWJ-20485, RWJ20485, ORF20485, ORF-20485, RWJ 20485, ORF 20485
T7724103475-41-8
Tepoxalin (RWJ 20485) is a 5-lipoxygenase inhibitor potentially for the treatment of asthma, osteoarthritis. Tepoxalin inhibits COX-1, COX-2, and 5-LOX. Tepoxalin is a potent inhibitor of sheep seminal vesicle cyclooxygenase (COX) (IC50 = 4.6 microM), rat basophilic leukemia cell (RBL-1) lysate COX (IC50 = 2.85 microM) and COX from intact RBL-1 cells (IC50 = 4.2 microM).
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