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t-26c

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  • Inhibitors & Agonists
    3
    TargetMol | Inhibitors_Agonists
T-26c
T5361869296-13-9
T-26c is a highly potent and selective matrix metalloproteinase-13 (MMP-13) inhibitor with an IC50 of 6.75 pM.
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A-893
T53811868232-32-9
A-893 is a cell-active inhibitor of Methyltransferase SMYD2 (IC50 = 2.8 nM).
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3-6 months
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T 26c disodium salt
T37860869298-22-6
Highly potent and selective MMP13 inhibitor (IC50 = 6.9 pM). Exhibits >2600-fold selectivity for MMP13 over related MMPs. Inhibits degradation of bovine nasal septum cartilage explants in vitro . Orally bioavailable. Nara et al (2014) Thieno[2,3-d]pyrimidine-2-carboxamides bearing a carboxybenzene group at 5-position: highly potent, selective, and orally available MMP-13 inhibitors interacting with the S1 binding site. Bioorg.Med.Chem. 22 5487 PMID:25192810
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6-8 weeks
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