t 326

HDAC3-IN-T326 is a potent and selective HDAC3 inhibitor that acts by increasing NF-κB acetylation and activating HIV gene expression in latent HIV-infected cells.

LCB 03-0110 Dihydrochloride is a potent inhibitor of the c-Src kinase (IC50 = 1.3 nM) and tyrosine kinases in the BTK and SYK family, as well as in the DDR2 family. It inhibits LPS-induced activation of macrophages and TGF-β1-induced activation of fibroblasts in vitro, inhibits activation of macrophages and fibroblasts, and inhibits scarring in wound healing models.

L-Clausenamide is an alkaloid extracted from the leaves of the yellow bark (Clausena lansium (Lour) skeels) and can be used to improve cognitive function. L-Clausenamide inhibits beta-amyloid (Aβ) toxicity and prevents the formation of neurofibrillary tangles by inhibiting tau phosphorylation. L-Clausenamide has neuroprotective activity and can be used to modulate stimuli triggered by Aβ25-35. L-Clausenamide can be used to study neurological disorders like Alzheimer's disease.

Phosphocreatine disodium (Phosphocreatine disodium salt) is a phosphorylated creatine molecule that serves as a rapidly mobilizable reserve of high-energy phosphates in muscle, skeletal, and brain.

Azathramycin (Desmethyl Azithromycin) is an antibiotic derived from erythromycin, binding to the 50S subunit of the bacterial ribosome, and thus inhibits translation of mRNA.

Lumefantrine (dl-Benflumelol) is an antimalarial agent used to treat acute uncomplicated malaria. It is administered in combination with artemether for improved efficacy. This combination therapy exerts its effects against the erythrocytic stages of Plasmodium spp. and may be used to treat infections caused by P. falciparum and unidentified Plasmodium species, including infections acquired in chloroquine-resistant areas.

Potassium guaiacolsulfonate hemihydrate (Potassium guaiacolsulfonate) is an aromatic sulfonic acid used in medicine as an expectorant.

Mildronate (Meldonium) is an inhibitor of biosynthesis of L-carnitine by gamma-butyrobetaine (GBB) hydroxylase and as a competitive inhibitor of renal carnitine reabsorption.

Metadoxine (Metadoxil) is a neurotransmitter stimulant.

Tosufloxacin tosylate hydrate (A-61827 tosylate hydrate) is a fluoroquinolone antibacterial agent that is used to treat susceptible infections.

Lemuteporfin is a light-activated photosensitizing agent that is rapidly internalized by viable cells, localizing within the cytoplasm and associating with mitochondria. This localization is a key characteristic that confers strong cytotoxic potential upon light activation. Lemuteporfin has demonstrated the ability to reduce sebaceous gland volume in preclinical animal studies. It is currently under investigation in relation to benign prostatic hyperplasia and in topical form for the management of androgenetic alopecia.

Tosufloxacin is a fluoroquinolone antibiotic used to treat susceptible infections.

(E)-3PO is a PFKFB3 (6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase) inhibitor.

Lavandulyl acetate is a component of lavender oil.

NVP-TNKS656 (TNKS656) is a highly potent, selective, and orally active TNKS2 inhibitor.

LBX192( NVP-LBX192) is a liver-targeted glucokinase activator.

Ledol ((+)-Ledol) is a naturally occurring sesquiterpene with potential biological activities such as antioxidant, anti-inflammatory, xanthine oxidase inhibition and uric acid reduction.

(6R,7S)-Cefminox sodium heptahydrate (Meicelin) is a broad-spectrum, bactericidal cephalosporin antibiotic, particularly effective against Gram-negative and anaerobic bacteria.

LEO-32731 is a bioactive chemical.

Leonoside B is a new phenylpropanoid glycoside from Leonurus glaucescens.

Etilefrine hydrochloride is a phenylephrine-related beta-1 adrenergic and alpha adrenergic agonist used as a cardiotonic and antihypotensive agent.

Lepidimoide is an allelopathic substance extracted from germinated cress (Lepirium sativum) seeds.

Leplinine (AIT-082, SPI-205) is a neurotrophic agent that may be used to treat Alzheimer's disease and spinal cord injury.

Leteprinim (AIT 082 acid) is an hypoxanthine derivative that stimulates in vitro neurite outgrowth and the production of adenosine and neurotrophins from astrocytes.