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By Target- Neurotensin Receptor
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Results for "
sr 142948 dihydrochloride
" in TargetMol Product Catalog- Inhibitors & Agonists1
SR 142948 dihydrochloride
T73677
SR 142948 dihydrochloride is a selective, orally active, non-peptide neurotensin receptor (NT) antagonist, featuring IC50 values of 1.19 nM, 0.32 nM, and 3.96 nM in h-NTR1-CHO cells, HT-29 cells, and adult rat brain, respectively. It effectively inhibits NT-induced inositol monophosphate formation in HT-29 cells (IC50 = 3.9 nM) and blocks NT-induced hypothermia, analgesia, and steering behavior in vivo. Furthermore, it demonstrates blood-brain barrier permeability, positioning it as a potential tool for psychiatric disorder research [1] [2].
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T23386184162-64-9
SR 142948 is a neurotensin (NT) receptor antagonist.
- $1,330
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