spdb sulfo

SPDB-sulfo, a glutathione-cleavable linker, is utilized in the development of antibody-drug conjugates (ADCs) [1].

NO2-SPDB-sulfo, a cleavable linker essential in ADC synthesis, connects cytotoxic drugs to antibodies, allowing targeted delivery to cells or proteins. Its cleavable nature ensures controlled drug release, optimizing the effectiveness of ADCs.

DMAC-SPDB-sulfo is a cleavable linker essential in ADC synthesis, enabling precise delivery of cytotoxic drugs to cells or proteins by attaching them to antibodies. Its cleavable nature ensures controlled drug release, optimizing ADC effectiveness.

Sulfo-SPDB-DM4 is a drug-linker conjugate designed for antibody-drug conjugates (ADCs) that employs the maytansine-based payload (DM4, an antitubulin agent) connected through the sulfo-SPDB linker.

sulfo-SPDB is a cleavable linker vital in ADC synthesis. sulfo-SPDB joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing ADC effectiveness.

Sulfo-SPDB-DGN462 is an agent-linker conjugate utilized for Antibody-Drug Conjugates (ADCs), featuring the potent DNA-alkylating agent DGN462 known for its anti-tumor properties, including efficacy against acute myeloid leukemia (AML), and is conjugated via the cleavable Sulfo-SPDB linker.