sn glycero 3 phosphocholine

sn-Glycero-3-phosphocholine (Choline glycerophosphate) is a natural choline compound found in the brain and in milk. It is also a parasympathomimetic acetylcholine precursor which may have a potential for the treatment of Alzheimer's disease and dementia. sn-Glycero-3-phosphocholine rapidly delivers choline to the brain across the blood–brain barrier and is a biosynthetic precursor of the acetylcholine neurotransmitter. It is a non-prescription drug in most countries due to its Generally Recognised As Safe (GRAS) status [1]. Studies have investigated its efficacy for cognitive disorders including stroke and Alzheimer's disease. An Italian multicentre clinical trial on 2, 044 patients suffering from recent stroke were supplied Glycerylphosphorylcholine in doses of 1, 000 mg/day for 28 days and 400 mg three times per day for the five ensuing months. The trial confirmed the therapeutic role of alpha-GPC on the cognitive recovery of patients based on four measurement scales, three of which reached statistical significance [2].

1-Docosahexaenoyl-sn-glycero-3-phosphocholine, an ester product, is a phospholipid containing DHA (docosahexaenoic acid), often used in biomedical research as an important source of omega-3 fatty acids.

1-Myristoyl-2-stearoyl-sn-glycero-3-phosphocholine is an endogenous metabolite. 1-Myristoyl-2-stearoyl-sn-glycero-3-phosphocholine is a non-limiting exemplary phosphatidyl choline.

1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine is an endogenous metabolite.

1-Arachidoyl-sn-glycero-3-phosphocholine is a lysophospholipid (LyP).

1-(1(Z)-Hexadecenyl)-2-linoleoyl-sn-glycero-3-phosphocholine is a plasmalogen characterized by the presence of 1(Z)-hexadecenoic acid and linoleic acid at the sn-1 and sn-2 positions, respectively. It counteracts lead-induced reductions in cell viability and suppresses increases in reactive oxygen species (ROS) and oxidized phospholipids in HepG2 hepatocytes. In dogs with myxomatous mitral valve disease, serum levels of this compound decrease when their diet is enriched with medium chain triglycerides, fish oil, carnitine precursors, magnesium, and antioxidants.

1-Heptadecanoyl-2-hydroxy-sn-glycero-3-phosphocholine, an endogenous metabolite present in blood, is utilized in research on pregnancy and sepsis [1] [2] [3].

1,2-Dibehenoyl-sn-glycero-3-phosphocholine (DBPC), a phospholipid integral to cell membranes, facilitates the formation of micelles, liposomes, and various artificial membranes [1].

1,2-Di-O-(9Z-octadecenyl)-sn-glycero-3-phosphocholine is a surfactant known for its role in promoting liposome formation. This compound is effective in studying the biological effects of ceramide and ceramide-1-phosphate. Additionally, it has significant applications in determining phospholipase A activity of lecithin-cholesterol acyltransferase within ether matrices.

PChemsPC (1-Palmitoyl-2-cholesterylhemisuccinoyl-sn-glycero-3-phosphocholine) is a sterol lipid that can stably separate into micron-scale liquid phases.

1,2-Dihexanoyl-sn-Glycero-3-Phosphocholine is a useful organic compound for research related to life sciences. The catalog number is TF0018 and the CAS number is 34506-67-7.

1-(1(Z)-Hexadecenyl)-2-palmitoleoyl-sn-glycero-3-phosphocholine is a plasmalogen characterized by the presence of 1(Z)-hexadecenoic acid and palmitoleic acid located at the sn-1 and sn-2 positions, respectively.

1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) is a phospholipid containing the unsaturated long-chain (18:1) oleic acid inserted at the sn-1 and sn-2 positions.

1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is a synthetic phospholipid utilized in liposomes for the study of lipid monolayers and bilayers.

1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine is an endogenous metabolite identified in the aging mouse brain.

1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (Palmitoyloleoylphosphatidylcholine) is a phospholipid commonly found in cell membranes, with cholesterol compositions ranging from 0 to 60 mol%.

15:0 PC (1,2-Dipentadecanoyl-sn-glycero-3-phosphocholine) is a type of phosphatidylcholine utilized for the preparation of giant unilamellar vesicles (GUV).

11:0 PC (1,2-Diundecanoyl-sn-glycero-3-phosphocholine) is a type of phosphatidylcholine that plays a role in the folding of intact, functional integral membrane proteins.

08:0 Lyso PC (1-Octanoyl-sn-glycero-3-phosphocholine) is a type of lysophosphatidylcholine that can be hydrolyzed by phospholipase A2.

18:0 Diether PC (1,2-Di-O-octadecyl-sn-glycero-3-phosphocholine) is a glycerophospholipid utilized as a non-hydrolyzable ether lipid in chlorophyll-containing vesicles.

06:0 Diether PC (1,2-Di-O-hexyl-sn-glycero-3-phosphocholine) is a glycerophospholipid that can be utilized for the preparation of bicelles.

DLPC is an LRH-1 agonist ligand. DLPC is a phospholipid for biological study[1][2].

Azelaoyl PAF is a potent PPARγ agonist that competitively binds thiazolidinediones with potency comparable to rosiglitazone. In atherosclerosis studies, Azelaoyl PAF promotes the uptake of oxidized low-density lipoprotein (oxLDL) by macrophages by upregulating CD36 expression. In fibroblasts from Friedreich's ataxia (FRDA) patients, Azelaoyl PAF significantly increased mRNA and protein levels of ferritin.

DHAPC (1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine) can be used as a fluorine-18 radiolabeling agent for PET imaging of prostate cancer.