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(3)
By Target- c-Met/HGFR
- Ligands for Target Protein for PROTAC(1)
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Results for "
sjf-8240
" in TargetMol Product Catalog- Inhibitors & Agonists4
- PROTAC Products4
SJF 8240
T362462230821-68-6
c-MET degrader. Comprises MET inhibitor foretinib (GSK 1363089; Cat. No. 6056) joined by a linker to a von Hippel-Lindau (VHL) recruiting ligand. Degrades c-MET within 6 hours in vitro. Inhibits agonist-driven AKT phosphorylation and GTL16 cell proliferation (IC50 = 66.7 nM). Also degrades exon-14-deleted c-MET in Hs746T cells.
- $1,060
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Iodine-C3-O-C3-PEG-Boc
T2120292230826-08-9
Iodine-C3-O-C3-PEG-Boc is a PROTAC linker (PROTAClinker) utilized in the synthesis of PROTACs, such as SJF-8240.
- Inquiry Price
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3-Fluoro-desmethyl-cabozantinib-C3-O-C3-PEG-acid
T2123662230826-10-3
3-Fluoro-desmethyl-cabozantinib-C3-O-C3-PEG-acid is a target protein ligand-linker conjugate combining a c-Met ligand with a PROTAC linker to recruit E3 ligase. It is applicable for synthesizing PROTACs, such as SJF-8240.
- Inquiry Price
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3-Fluoro-desmethyl-cabozantinib
T212453849217-50-1
3-Fluoro-desmethyl-cabozantinib is a BCL6 ligand utilized in the synthesis of PROTACs, such as SJF-8240.
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