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sirreal1 o propargyl

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
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    TargetMol | PROTAC
SirReal1-O-propargyl
PROTAC Sirt2-binding moiety 1
T186411862237-99-7
SirReal1-O-propargyl, a moiety based on SirReal1, is a selective and highly potent inhibitor of Sirtuin 2 (Sirt2), demonstrating an IC50 of 2.4 μM. It operates by binding to the cereblon ligand through a linker, facilitating the formation of PROTAC for the degradation of Sirt2[1].
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