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By Target- PROTACs
- Sirtuin(1)
- Others(2)
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Results for "
sirreal-1
" in TargetMol Product Catalog- Inhibitors & Agonists3
- PROTAC Products2
sirreal-1
SirReal 1
T24790801227-82-7
SirReal-1 is an effective and selective inhibitor of Sirt2.
- $1,520
Size
QTY
PROTAC Sirt2 Degrader-1
T166672098487-75-1
PROTAC Sirt2 Degrader-1 is a SirReal-based PROTAC that acts as a Sirt2 degrader, composed of a highly potent and isotype-selective Sirt2 inhibitor, a linker, and a bona fide cereblon ligand for E3 ubiquitin ligase. PROTAC Sirt2 Degrader-1 shows an IC50 of 0.25 μM for Sirt2, with no effect on Sirt1 Sirt3 (IC50s > 100 μM)[1].
- Inquiry Price
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QTY
SirReal1-O-propargyl
PROTAC Sirt2-binding moiety 1
T186411862237-99-7
SirReal1-O-propargyl, a moiety based on SirReal1, is a selective and highly potent inhibitor of Sirtuin 2 (Sirt2), demonstrating an IC50 of 2.4 μM. It operates by binding to the cereblon ligand through a linker, facilitating the formation of PROTAC for the degradation of Sirt2[1].
- Inquiry Price
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