scandoside

Scandoside, a cyclic enolide that can be isolated from Haemophilus difficile, exhibits anti-inflammatory activity, inhibits the expression levels of inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), TNF-α, and IL-6 messenger RNA (mRNA), and inhibits the nuclear transcription factor, kappa-B alpaha (IκB-α), p38, extracellular signal-regulated kinase (ERK) and c-Jun N-terminal kinase (JNK) inhibitor phosphorylation.

(E)-6-O-(p-coumaroyl)scandoside methyl ester shows moderate anti-proliferation effect on PC3 human androgen-independent prostate cancer cells.

10-O-trans-p-coumaroylscandoside is a useful organic compound for research related to life sciences and the catalog number is T124045.

10-O-trans-p-Feruloylscandoside is a useful organic compound for research related to life sciences and the catalog number is T125880.

6-O-Acetylscandoside is a useful organic compound for research related to life sciences and the catalog number is T126269.

6-O-Methylscandoside methyl ester is a natural product that can be used in related research in the field of life sciences. Its product number is TN8739.

Oldenlandoside I ((E)-6-O-p-coumaroyl scandoside methyl ester) is a natural product isolated from Hedyotis diffusa exhibiting potential antiproliferative activity. It induces apoptosis in SKM-1 cells in combination with p-coumaric acid, associated with caspase activation and inhibition of PI3K/Akt pathway proteins.