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By Target- Apoptosis
- FGFR(1)
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Results for "
rpt-835
" in TargetMol Product Catalog- Inhibitors & Agonists1
Alofanib
RPT835
T51221612888-66-0
Alofanib (RPT835) is a selective allosteric inhibitor of FGFR2 and has a dramatic inhibitory effect on FGF2-induced phosphorylation of FRS2a in KATO III cells (IC50 <10 nM). It has no direct effect on FGF2-dependent FGFR1 and FGFR3 phosphorylation levels in either cell lines and no effects on FGF2-FGFR2 binding.
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