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rorc2

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  • Inhibitors & Agonists
    2
    TargetMol | Inhibitors_Agonists
ROR agonist-1
T127502361528-74-5
ROR agonist-1 is a potent and orally bioavailable inverse agonist of the retinoic acid receptor-related orphan receptor C2 (RORC2), demonstrating inhibition of IL-17A production from human primary TH17 cells with a pIC50 of 7.5.
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6-8 weeks
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PF-06747711
T164951892576-58-7
PF-06747711 is an effective and selective retinoic acid receptor-related orphan C2 inverse agonist (IC50: 4.1 nM). PF-06747711 also has anti-skin inflammatory activity.
    7-10 days
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