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By Target- RIP kinase
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Results for "
ripk1-in-4
" in TargetMol Product Catalog- Inhibitors & Agonists5
RIPK1-IN-4 
T127301481641-08-0In house
RIPK1-IN-4 is a potent and selective type II kinase receptor interacting protein 1 (RIP1) kinase inhibitor and binds to a DLG-out inactive form of RIP1 (IC50s of 16 nM and 10 nM for RIP1 and ADP-Glo kinase).
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RIPK1-IN-7
T127312300982-44-7
RIPK1-IN-7 is a potent and selective inhibitor of RIPK1 (Kd of 4 nM and enzymatic IC50 of 11 nM), exhibiting excellent antimetastasis activity in the experimental B16 melanoma lung metastasis model.
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RIPK1-IN-8
T634692319663-07-3
RIPK1-IN-8 is an aminoimidazolopyridine and is a selective and potent inhibitor of RIPK1 (IC50: 4 nM).RIPK1-IN-8 has research potential in inflammatory diseases.
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Necroptosis-IN-4
T89380
Necroptosis-IN-4 is an effective inhibitor of necroptosis, specifically targeting RIP kinase 1 (RIPK1) without inhibitory activity against RIPK3. It exhibits weak inhibitory effects on VEGFR1 2 and PDGFR-α.
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Necrostatin-34
2-{[3-cyano-4-(4-methylphenyl)-6-oxo-1,4
T9095375835-43-1
Necrostatin-34 (2-{[3-cyano-4-(4-methylphenyl)-6-oxo-1,4) is a RIPK1 kinase inhibitor, stabilizing RIPK1 kinase in an inactive conformation by occupying a distinct binding pocket in the kinase domain.
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