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reveromycin b

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Reveromycin B
T38044144860-68-4
Reveromycin B is a spiroketal bacterial metabolite originally isolated from Streptomyces. It inhibits EGF-induced mitogenic activity in Balb MK cells (IC50 = 6 μg ml) and exhibits pH-dependent antifungal activity against C. albicans [MICs = 15.6 and >500 μg ml at pH 3.0 and 7.4, respectively]. Unlike reveromycin A and reveromycin C, reveromycin B does not inhibit the proliferation of KB and K562 cells.
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