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Search Results for " retinitis "

Targets

11

Compounds

16

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T0220 Foscarnet sodium Phosphonoformate Virus Protease , Reverse Transcriptase , DNA/RNA Synthesis
Foscarnet sodium (Phosphonoformate) is an antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesviruses and HIV.
T6244 Cidofovir HPMPC,GS 0504,(S)-HPMPC Others , DNA/RNA Synthesis
Cidofovir ((S)-HPMPC) inhibits virus replication by specific inhibition of viral DNA synthesis.
T8736 Cidofovir dihydrate HPMPC,(S)-HPMPC,GS 0504 Others
Cidofovir dihydrate (HPMPC) is an anti-CMV drug, It can suppress CMV replication by selective inhibition of viral DNA polymerase and therefore prevention of viral replication and transcription. Cidofovir dihydrate is an ...
T34921L1 Tresperimus TFA Tresperimus TFA(160677-67-8 Free base) Others
Tresperimus TFA can be used as an immune agent and can be used to study retinitis.
T9289 Phosphonoformic acid trisodium salt hexa Sodium phosphonatoformate hexahydrate,foscarnet sodium hexahydrate Others
Phosphonoformic acid trisodium salt hexa (Sodium phosphonatoformate hexahydrate) is an antiviral drug for the treatment of CMV retinitis.
T22282 Brr2-IN-3 Brr2 Inhibitor 9,Brr2 Inhibitor C9 Others
Brr2-IN-3 (Brr2 Inhibitor C9) is an allosteric inhibitor of the spliceosomal RNA helicase Brr2. Brr2 is implicated in autosomal-dominant retinitis pigmentosa (a group of progressive retinal degenerative disorders).
T39068 Fomivirsen sodium
Fomivirsen sodium is an antisense 21 mer phosphorothioate oligonucleotide. Fomivirsen is an antiviral agent that is used cytomegalovirus retinitis (CMV) research, incluiding in AIDs. Fomivirsen sodium binds to and degrad...
T71066 Cidofovir sodium
Cidofovir sodium is the salt form of Cidofovir, a Cytomegalovirus Nucleoside Analog DNA Polymerase Inhibitor that is an injectable antiviral medication primarily used as a treatment for cytomegalovirus (CMV) retinitis in...
T36570 KUS121
KUS121 is a valosin-containing protein (VCP) modulator that inhibits VCP ATPase activity (IC50= 330 nM).1It inhibits cell death, ATP depletion, and upregulation of C/EBP-homologous protein (CHOP) induced by tunicamycin, ...
TP2199 Rhodopsin peptide Others
Rhodopsin peptide is a peptide with the sequence H2N-Val-Ser-Lys-Thr-Glu-Thr-Ser-Gln-Val-Ala-Pro-Ala-OH, MW= 1217.33. Rhodopsin is a biological pigment in photoreceptor cells of the retina that is responsible for the fir...
T78594 (Z)-KC02
(Z)-KC02 is an ABHD16A inhibitor which targets the enzyme responsible for producing lysophosphatidylserine (lyso-PS), a lipid involved in regulating immune and neurological functions. This compound is linked to the mitig...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-01203 RP2 Protein, Human, Recombinant (GST) Human Baculovirus-Insect Cells
XRP2, also known as Protein XRP2 and RP2, is a member of the TBCC (tubulin cofactor C) family and contains one C-CAP/cofactor C-like domain. This protein is encoded by the RP2 gene in humans. XRP2 stimulates the GTPase a...
TMPY-00882 Mer Protein, Human, Recombinant (His & hFc) Human HEK293
Proto-oncogene tyrosine-protein kinase MER (MERTK) is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-li...
TMPY-04330 Mer Protein, Human, Recombinant Human HEK293
Proto-oncogene tyrosine-protein kinase MER (MERTK) is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-li...
TMPJ-00278 Clusterin Protein, Human, Recombinant (hFc & His) Human Human Cells
Clusterin is a secreted protein which belongs to the Clusterin family. Clusterin is expressed in adult testis, heart, ovary, adrenal gland, brain and liver. Clusterin has been suggested to be involved in several basic bi...
TMPJ-00279 Clusterin Protein, Human, Recombinant (His) Human Human Cells
Clusterin is a secreted protein which belongs to the Clusterin family. Clusterin is expressed in adult testis, heart, ovary, adrenal gland, brain and liver. Clusterin has been suggested to be involved in several basic bi...
TMPY-03109 PHYH Protein, Human, Recombinant Human E. coli
PHYH belongs to the family of iron(II)-dependent oxygenases, which typically incorporate one atom of dioxygen into the substrate and one atom into the succinate carboxylate group. PHYH is expressed in liver, kidney, and ...
TMPY-03690 CD133/PROM1 Protein, Rat, Recombinant (mFc) Rat HEK293
CD133, also known as PROM1 and Prominin 1, is a pentaspan transmembrane glycoprotein that belongs to the prominin family. It localizes to membrane protrusions and is often expressed on adult stem cells. CD133 is known to...
TMPY-03691 CD133/PROM1 Protein, Rat, Recombinant (His) Rat HEK293
CD133, also known as PROM1 and Prominin 1, is a pentaspan transmembrane glycoprotein that belongs to the prominin family. It localizes to membrane protrusions and is often expressed on adult stem cells. CD133 is known to...
TMPJ-01143 MERTK/Mer Protein, Human, Recombinant (aa 1-323, His) Human Human Cells
Tyrosine-protein kinase Mer (MERTK) is a single-pass type I membrane protein which belongs to the MER/AXL/TYRO3 receptor kinase family. MERTK include two fibronectin type-III domains, two Ig-like C2-type domains, and one...
TMPY-02291 Mer Protein, Mouse, Recombinant (hFc) Mouse HEK293
Proto-oncogene tyrosine-protein kinase MER (MERTK) is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-li...
TMPY-02176 Harmonin/USH1C Protein, Human, Recombinant (His) Human E. coli
Harmonin, also known as Antigen NY-CO-38 / NY-CO-37, Autoimmune enteropathy-related antigen AIE-75, Protein PDZ-73, Renal carcinoma antigen NY-REN-3, Usher syndrome type-1C protein and USH1C, is a protein that is express...
TMPY-04437 Mer Protein, Mouse, Recombinant (His & GST) Mouse Baculovirus-Insect Cells
Proto-oncogene tyrosine-protein kinase MER (MERTK) is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-li...
TMPY-04363 Mer Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
Proto-oncogene tyrosine-protein kinase MER (MERTK) is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-li...
TMPY-04747 Mer Protein, Human, Recombinant (aa 578-872) Human Baculovirus-Insect Cells
Proto-oncogene tyrosine-protein kinase MER (MERTK) is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-li...
TMPY-01857 SEMA4A Protein, Human, Recombinant (His) Human HEK293
Semaphorin-4A, also known as Semaphorin-B, SEMA4A, Sema B and SEMAB, is a single-pass type I membrane protein that belongs to the semaphorin family. It inhibits axonal extension by providing local signals to specify terr...
TMPY-02006 SEMA4A Protein, Human, Recombinant (hFc) Human HEK293
Semaphorin-4A, also known as Semaphorin-B, SEMA4A, Sema B and SEMAB, is a single-pass type I membrane protein that belongs to the semaphorin family. It inhibits axonal extension by providing local signals to specify terr...
RP2 Protein, Human, Recombinant (GST)
TMPY-01203
Species: Human
Expression System: Baculovirus-Insect Cells
Mer Protein, Human, Recombinant (His & hFc)
TMPY-00882
Species: Human
Expression System: HEK293
Mer Protein, Human, Recombinant
TMPY-04330
Species: Human
Expression System: HEK293
Clusterin Protein, Human, Recombinant (hFc & His)
TMPJ-00278
Species: Human
Expression System: Human Cells
Clusterin Protein, Human, Recombinant (His)
TMPJ-00279
Species: Human
Expression System: Human Cells
PHYH Protein, Human, Recombinant
TMPY-03109
Species: Human
Expression System: E. coli
CD133/PROM1 Protein, Rat, Recombinant (mFc)
TMPY-03690
Species: Rat
Expression System: HEK293
CD133/PROM1 Protein, Rat, Recombinant (His)
TMPY-03691
Species: Rat
Expression System: HEK293
MERTK/Mer Protein, Human, Recombinant (aa 1-323, His)
TMPJ-01143
Species: Human
Expression System: Human Cells
Mer Protein, Mouse, Recombinant (hFc)
TMPY-02291
Species: Mouse
Expression System: HEK293
Harmonin/USH1C Protein, Human, Recombinant (His)
TMPY-02176
Species: Human
Expression System: E. coli
Mer Protein, Mouse, Recombinant (His & GST)
TMPY-04437
Species: Mouse
Expression System: Baculovirus-Insect Cells
Mer Protein, Human, Recombinant (His & GST)
TMPY-04363
Species: Human
Expression System: Baculovirus-Insect Cells
Mer Protein, Human, Recombinant (aa 578-872)
TMPY-04747
Species: Human
Expression System: Baculovirus-Insect Cells
SEMA4A Protein, Human, Recombinant (His)
TMPY-01857
Species: Human
Expression System: HEK293
SEMA4A Protein, Human, Recombinant (hFc)
TMPY-02006
Species: Human
Expression System: HEK293
TargetMol