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By Target- Apoptosis
- HDAC(1)
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Results for "
r306465
" in TargetMol Product Catalog- Inhibitors & Agonists2
R306465
JNJ 16241199, JNJ16241199, JNJ-16241199, R-306465, R 306465
T21324604769-01-9In house
R306465 (JNJ-16241199) is an orally active and selective class I histone deacetylase (HDAC 1) inhibitor with an IC50 of 3.3 nM. R306465 has a broad spectrum of antitumor activity, can induce histone 3 acetylation, and induce apoptosis, and can be used to study solid tumors and hematological malignancies.
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Gemcitabine monophosphate
GemMP, Gemcitabine 5′-phosphate
T21329116371-67-6
R306465 is a novel HDAC inhibitor with broad-spectrum antitumor activity against solid (IC50: 30 to 300 nM) and hematological malignancies. R306465 was found to be a potent inhibitor of HDAC1 and -8 (class I) in vitro.
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