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Results for "
pyridomycin
" in TargetMol Product Catalog- Inhibitors & Agonists2
Pyridomycin
T3707018791-21-4
Pyridomycin is a structurally unusual antimycobacterial cyclodepsipeptide whose composition includes two rare moieties: 3-(3-pyridyl)-L-alanine and 2-hydroxy-3-methylpent-2-enoic acid. It inhibits NADH-dependent enoyl (Acyl-Carrier-Protein) reductase InhA, preventing mycolic acid synthesis in M. tuberculosis, including isoniazid-resistant strains (MICs = 0.31-0.63 μg ml).
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BDM91514
T792722892824-90-5
BDM91514 enhances antibiotic efficacy by inhibiting AcrB, effectively curbing the proliferation of E. coli BW25113 with an EC90 of 8 μM when coupled with 8 μg mL Pyridomycin. Additionally, BDM91514 exhibits favorable plasma and microsomal stability [1].
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