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ptdins-(3,4,5)-p3-biotin

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PtdIns-(3,4,5)-P3-biotin (sodium salt)
PtdIns-(3,4,5)-P3-biotin (sodium salt)
T370291415684-80-8
The PtdIn phosphates play an important role in the generation and transduction of intracellular signals. PtdIns-(3,4,5)-P3-biotin is an affinity probe which allows the PIP3 to be detected through an interaction with the biotin ligand. This design allows PtdIns-(3,4,5)-P3-biotin to serve as a general probe for any protein with a high affinity binding interaction with inositol-(3,4,5)-triphosphate phospholipids, such as phosphatidylinositol 3-kinase, PTEN, or PH-domain-containing proteins.
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