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protoescigenin

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  • Inhibitors & Agonists
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Protoescigenin
TN210720853-07-0
Protoescigenin is from horse chestnut saponin mixture and can be used as the substrate for exploratory chemistry towards selective protection.
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Protoescigenin 21-tiglate
(E)-21-Angeloyl-protoaescigenin
TN81137047-43-0
Protoescigenin 21-tiglate (compound 10), a type of Bayberry Triterpenoid Saponin (BAT), can be isolated from the acidic hydrolyzed products (AHP) of a crude extract derived from bayberry seeds. BATs are generally known for their robust anti-tumor, anti-inflammatory, and anti-Alzheimer's activities. However, the anti-tumor activity of Protoescigenin 21-tiglate is relatively weak, with inhibitory concentrations (IC50) exceeding 80 μM for MCF-7 and at 80 μM for HeLa cells.
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21-Angeloyl-protoaescigenin
(Z)-Protoescigenin 21-tiglate
TN811635931-54-5
21-Angeloyl-protoaescigenin (compound 11) is a bryophyte analogous triterpene (BAT) that can be isolated from the acidic hydrolysis products (AHP) of crude bryophyte seed extracts. BATs are known for their potent antitumor, anti-inflammatory, and anti-Alzheimers activities. However, Protoescigenin 21-tiglate exhibits antitumor activity, showing inhibition efficacy (IC50) of 38.2 μM and 33 μM against MCF-7 and HeLa cells, respectively.
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