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Results for "
protac ido1 degrader1
" in TargetMol Product Catalog- Inhibitors & Agonists1
- PROTAC Products1
PROTAC IDO1 Degrader-1
PROTAC IDO1 Degrader-1
T373292488851-89-2
PROTAC IDO1 Degrader-1, a pioneering compound, efficiently targets indoleamine 2,3-dioxygenase 1 (IDO1) for ubiquitination and degradation by recruiting IDO1 to the CRBN E3 ligase, thereby facilitating its entry into the ubiquitin-proteasome system (UPS) with a DC50 of 2.84 μM. This compound also moderately enhances the tumor-killing efficacy of HER2 CAR-T cells[1].
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