praziquantel

Praziquantel (Droncit) increases the permeability of the tegument of susceptible worms, resulting in an influx and increase in intra-tegumental calcium leading to rapid contractions and paralysis of the worm's musculature through a subsequent increase in levels of calcium in the sarcoplasmic reticulum. Praziquantel is a pyrazinoisoquinoline derivative with anthelminthic property. In addition, vacuolization of the tegumental syncytium and blebbing results in tegument disintegration, leads to antigen exposure and elicit host defense responses to the worm.

(R)-Praziquantel D11 is the deuterium labeled (R)-Praziquantel. (R)-Praziquantel is the active enantiomer of Praziquantel, is a partial the human 5-HT2B receptor agonist

Praziquantel D11 is the deuterium labeled Praziquantel, and is an agent of anthelmintic.

(R)-Praziquantel is an active enantiomer of praziquantel.

(S)-Praziquantel-d11 is a deuterated compound of (S)-Praziquantel. (S)-Praziquantel has a CAS number of 57452-97-8.

Praziquanamine is a compound related to praziquantel, which is used in the treatment of parasitic worm infections.